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Showing 1 to 1 of 1 for “"GRK3 G protein-coupled receptor kinase 3"”.
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Grk3 Connects Angiogenesis and Neuroendocrine Differentiation In Prostate Cancer By Activating Hdac2 That Epigenetically Represses Tsp1 and Rest
… patient prostate tumors. We also found that G-protein coupled receptor kinase 3 (GRK3) is a critical regulator of both angiogenesis and neuroendocrine differentiation. GRK3 expression is pronouncedly elevated in NEPC tumors from GEM models and patients. GRK3 downregulates REST (the master …