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Showing 1 to 1 of 1 for “"GRAMD1"”.

  1. Autogramin-2, a synthetic sterol, inhibits T cell adhesion and effector function

    Patommel, Katharina AliceUniversity of Cambridge2024

    Plasma membrane resident cholesterol is a key regulator of T cell immunity as it stabilises immune synapses, thus supporting effector T cell function. Recent publications suggest that increasing plasma membrane cholesterol content boosts anti-viral and anti-cancer immunity in T cells. Inhibition of …

    cambridge Repository record