Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 7 of 7 for “"GProtein"”.
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RATE-LIMITING STEP OF CONE PHOTOTRANSDUCTION RECOVERY AND OGUCHI DISEASE MECHANISMS
… stimuli. Phototransduction is mediated through a Gprotein signaling cascade. Light absorption by visual pigment triggers the isomerization of 11- cis-retinal covalently attached to these pigments, which are heptahelical transmembrane Gprotein- coupled receptors. Isomerization of 11-cis-retinal to …
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The Cloning and Characterization of Two ROP/RAC G-Proteins from Gossypium Hirsutum
… subfamilies III and IV of the plant monomeric Gprotein family. In this project, members of subfamilies II and I were cloned, sequenced, and named GhRac2 and GhRac3, respectively. Using real-time reverse transcription PCR, expression of GhRac2 was highest during fiber elongation, decreasing …
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Novel interactions of the 5-HT₂ₐ and related receptors with intracellular signalling proteins
… of the 5-HT₂ₐ and related receptors. The Gprotein coupled receptors (GPCRs) are named after their ability to interact with and signal through the trimeric G-proteins. The 5-hydroxytryptamine 2A receptor (5- HT₂ₐR) is a member ofthe group I family of rhodopsin-related GPCRs. The receptor is …
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Differentielle Genexpression in der Insulinoma-Zelllinie RINm5F nach Stimulation mit Leptin
… protein), fibrinogen-beta and RGS4 (regulator of Gprotein signalling 4). To the second group was assigned: PAP1 (pancreatitis associated protein 1), and to the third group tPA (tissue plasminogen activator), Ppap2a (phosphatidate phosphohydrolase type 2a), SOD2 (superoxide dismutase 2), …
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Pharmacological profiling of novel melanocortin peptides targeting the hMC1, hMC3 and hMC5 receptors in 2-D and 3-D models of activated chondrocytes
… via the activation of the 7-transmembrane Gprotein coupled melanocortin receptors. To date, five human melanocortin (hMC) receptors have been identified (hMC1 - hMC5), whereby, hMC1, hMC3 and hMC5 receptor subtypes display potent anti-inflammatory effects modulating inflammatory pathways …
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Neuropeptid Y- und Prionprotein- spezifische Aptamere
… NPY-Konformationen an die einzelnen GProtein gekoppelten NPY-Rezeptorsubtypen (Y1, Y2, Y3, Y4, Y5 und Y6) unterschiedliche Signale vermittelt werden können. Dieses differentielle Bindungsverhalten von NPY an seine Rezeptorsubtypen ist bisher unvollständig verstanden. Die in dieser …
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Characterization of Rimonabant effects on G protein activity
G protein-coupled receptor (GPCRs) is the largest class of cell-surface receptors, and represents today the target of 40% of the drugs in the pharmaceutical market. In the absence of agonists, many GPCRs have found to exhibit spontaneous activity, which can be blocked by ligands that are referred …