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Showing 1 to 3 of 3 for “"GPRC5A"”.
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The Role of Tyrosine Phosphorylation In The Functions of The Tumor Suppressor Gprc5A
… coupled receptor family C group 5 type A (GPRC5A) is expressed preferentially in normal lung tissue but its expression is suppressed in the majority of human non-small cell lung cancer cell lines and tissues. This differential expression has led to the idea that GPRC5A is a potential tumor …
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Loss of Gprc5A Enhances Survival In Normal and Malignant Lung Epithelial Cells By Eliciting Persistent Stat3 Activation Induced By Autocrine Lif
… receptor, family C, group 5, member a (Gprc5a) gene develop lung tumors indicating that Gprc5a is a tumor suppressor. In the present study, we examined he mechanism of Gprc5a-mediated tumor suppression. We found that epithelial cells from <em>Gprc5a</em> knockout mouse lung …
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Development of Improved Genetic Methods for Enterococcus Faecium
… the orphan human G-protein-coupled receptor, GPRC5A. Furthermore, using dsDNA recombineering, I generated HA-tagged and knockouts of E. faecium bile acid salt hydrolase to genetically confirm E. faecium's interactions with bile acids. The general RecT-mediated recombineering methods described …