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Showing 1 to 5 of 5 for “"GPI anchoring"”.

  1. Biological studies of GPI-anchoring in Trypanosoma cruzi

    Michele Anne ZacksThe University of Texas Medical Branch2007

    … membrane by\r\nglycosylphosphatidylinositol (GPI) anchors and play roles in host cell attachment and\r\ninvasion, and in parasite differentiation and replication. In other organisms, a\r\ntransamidase, GPI8, is involved in this anchoring process. This study investigated the\r\neffects of …

    utmb Repository record

  2. Isolation and molecular genetic analysis of conditionally lethal yeast mutants in glycosylphosphatidylinositol anchoring

    Leidich, Steven DonaldUniversity of Illinois at Urbana-Champaign2011

    Glycosylphosphatidylinositol (GPI) anchors are a recently described class of glycolipids attached through covalent linkage to protein. To explore the functions of GPIs, I investigated the effects of GPI anchoring deficiencies in the unicellular eukaryote Saccharomyces cerevisiae.

    uiuc Repository record

  3. Complexity of the Late Stages of GPI Anchor Biosynthesis in Saccharomyces Cerevisiae

    Taron, Christopher HenryUniversity of Illinois at Urbana-Champaign2015

    … to the third mannose of the mammalian GPI anchor. Genetic disruption of the yeast PIG-F gene (termed GPI11), demonstrated that it is essential for vegetative growth. Yeast gpi11 mutants in which the Gpi11 protein (Gpi11p) could be conditionally depleted were constructed and tested for …

    uiuc Repository record

  4. Development And Optimization Of The First High Throughput In Vitro Fret Assay To Characterize The Saccharomyces Cerevisiae Gpi-T

    Amarasingha Ekanayaka, Sandamali2013

    … TO CHARACTERIZE THE SACCHAROMYCES CEREVISIAE GPI TRANSAMIDASE</p> <p>By</p> <p>SANDAMALI AMARASINGHA EKANAYAKA</p> <p>December 2013</p> <p>Advisor: Dr. Tamara L. Hendrickson</p> <p>Major: Biochemistry</p> <p>Degree: Doctor of Philosophy</p> <p>The enzyme glycosylphosphatidylinositol …

    wayne-thes Repository record

  5. Biochemical And Structural Characterization Of The Core Subunits Of Gpi Transamidase

    G. Gamage, Dilani2014

    … CHARACTERIZATION OF THE CORE SUBUNITS OF GPI TRANSAMIDASE</p> <p>by</p> <p>DILANI G GAMAGE</p> <p>May 2015</p> <p>Advisor: Prof. Tamara L. Hendrickson</p> <p>Major: Chemistry (Biochemistry)</p> <p>Degree: Doctor of Philosophy</p> <p>Glycosylphosphatidylinositol transamidase (GPI-T) is a …

    wayne-thes Repository record