Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"GPER1"”.
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G protein-coupled receptor regulation: The role of protein interactions and receptor trafficking
… increased vascular permeability, and pain. GPER1 (G protein-coupled estrogen receptor 1) has recently been suggested as a novel estrogen receptor. Much controversy surrounds this receptor regarding its subcellular localization and activation. The aim of the present thesis was to explore the …
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Estrogenic modulation of excitatory synaptic transmission at hippocampal temporoammonic-CA1 synapses
… at these synapses involves activation of ERα and GPER1 as selective agonists of these receptors mimic the effects of E2 at TA-CA1 synapses. However, E2-induced LTP does not involve ERβ, and ERβ-selective agonists do not alter excitatory synaptic transmission at TA-CA1 synapses. ERα-mediated LTP …
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Viral- and host-targeted interventions to improve influenza disease outcomes
… G-protein coupled estrogen receptor 1 (GPER1) as a candidate regulator. Our subsequent experiments demonstrated that blocking GPER1 function with a selective antagonist lead to prolonged IFN signaling, whereas activation with a selective agonist was capable of suppressing signaling. …