Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 2 of 2 for “"GNPAT"”.
-
Deciphering Cancer Metabolic Dependencies in the Tumor Microenvironment
… upon CHP1 loss, the peroxisomal enzyme, GNPAT, partially compensates for the loss of ER lipid synthesis, enabling cell proliferation. Loss of CHP1 severely reduces fatty acid incorporation and storage in mammalian cells and invertebrates. Depletion of Chp1 and Gpat4 in the mouse liver …
-
Biochemical characterization of the first step in ether lipid biosynthesis: acylation of dihydroxyacetone phosphate
Glycerolipid biosynthesis is essential for cellular growth and proliferation. It is an indispensable pathway in many living organisms. In mammals four GPAT isoforms are known to catalyze the first step in glycerolipid biosynthesis which involves acylation of glycerol-3-phosphate to lysophosphatidic …