Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 7 of 7 for “"GMCSF"”.
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Membrane-Bound Immunomodulators As Adjuvants In A Cell Culture-Based Avian Influenza Vaccine
… in a chicken model using membrane-bound C3d, GMCSF, IL2 and IL4 as adjuvants. GMCSF adjuvanted vaccines delivered subcutaneously and C3d adjuvanted vaccines delivered subcutaneously and intranasally resulted in significantly higher antibody titers than vaccinating with inactivated virus alone. …
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Monocyte Derived Dendritic Cells: Sentinels and Translators of Immune Response to Staphylococcus aureus
… colony stimulating factor (GMCSF) and tumor necrosis factor-α (TNF-α) gene transcription. We continued our studies to identify the role of TNF-α in the LSA induced differentiation of monocyte to MonoDC. Blocking TNF-α reduced the expression of CD11c and increased the …
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Role of dendritic cells in response to cytokine gene adjuvants
… cytokine gene adjuvants to recruit DC, such as GMCSF and IL-3. The aim of the work carried out in this thesis was to investigate the effects of GM-CSF and IL-3 after gene-gun vaccination. Initial studies focused on the histological effects of GM-CSF and IL-3 in ovine skin. GM-CSF induced a …
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Einfluß von Wachstumsfaktoren und Wachstumsfaktorkombinationen auf Angio- und Arteriogenese am ischämischen Kaninchenmyokard : eine histologische Studie
… bei allen Einzelfaktorgruppen, VEGF, FGF sowie GMCSF, eine signifikante Steigerung der Kapillardichte, sowohl im Vergleich zur Ischämiegruppe als auch im Vergleich zur Placebogruppe. Die Arteriolenzahl stieg ebenfalls signifikant in allen Einzelfaktorgruppen im Vergleich zur Ischämiegruppe. Die …
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Gene Therapy Using Tet-Repressor System to Modulate Prostate Tumor Microenvironment
… TRAMPC2 cells did not grow <em>in vivo</em> and GMCSF transfected TRAMPC2 cells failed to grow tumors after <em>in vitro</em> passages, using <em>in vitro </em>assays we showed that these molecules reversed the inhibition of DC maturation induced by TRAMPC2 cells.</p>
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Klonering en uitdrukking van die mensgeen vir interleukin-3 (IL-3)
… secondary hematopo"ietic failure. The genes for GMCSF, G-CSF and IL-5 have already been successful cloned and expressed in our laboratory. As IL-3 has great therapeutic potential and because of the dependance of the above mentioned factors on IL-3 for greater therapeutic success we decided to …
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The A2A adenosine receptor: its role in suppressing vascular inflammation and its regulation by phosphorylation
… cytokines TNF-alpha, IL-6, IL-1 beta and GMCSF compared to wild-type mice. Consistent with this finding, heightened activation of the NF kappa B and JAK/STAT pathways was detected in aortic protein samples from A2AAR-deficient mice as demonstrated by increased levels of the phosphorylated …