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Showing 1 to 2 of 2 for “"GM130"”.

  1. Characterising the factors involved in ER-to-Golgi anterograde trafficking

    … that two long coiled-coil proteins, GMAP210 and GM130, are able to capture vesicles arriving from the ER. The mechanism by which these two proteins recognise other membranes is unclear. To study the role of GM130, I generated a stable GM130 knockout cell line using CRISPRCas9 gene editing, and …

    cambridge Repository record for Characterising the factors involved in ER-to-Golgi anterograde trafficking (opens in a new tab)

  2. Investigating the neuroprotective role of carboxyl-terminus of Hsc70-interacting protein (CHIP) in healthy aging

    … wild-type and CHIP knock-out cells stained with GM130. Western blotting was performed on several proteins involved in retrograde transport pathways, including COG complex as well as Rab proteins. In CHIP-null cells and animals, aberrant protein expression was correlated with increased Golgi …

    edinburgh Repository record for Investigating the neuroprotective role of carboxyl-terminus of Hsc70-interacting protein (CHIP) in healthy aging (opens in a new tab)