Global ETD Search

Novel strategies to increase Sirtuin-1 activity in aortic aneurysm

Liu, Hanxiao2022

… (3M SirT1) or overexpressing glutaredoxin-1 (Glrx), an enzyme that prevents oxidative modifications on SirT1, was able to restore SirT1 activity in liver cells. OBJECTIVES: The goal of this study is to enhance SirT1 activity in aortas and VSM cells in a mouse model of AA (hypomorphic …

bu Repository record for Novel strategies to increase Sirtuin-1 activity in aortic aneurysm (opens in a new tab)

Microenvironmental and metabolic influences in tumor cell redox homeostasis

Leslie, Matthew ThomasUniversity of Illinois at Urbana-Champaign2018

… RAS-transformed tumor cells expressing the Glrx-roGFP2 redox biosensor, a GFP-based subcellular probe sensitive to local glutathione redox potentials, were exposed to glutamine deprivation and pharmacologic inhibition of glutaminolytic enzymes. We found that oncogenic RAS increases cellular …

uiuc Repository record for Microenvironmental and metabolic influences in tumor cell redox homeostasis (opens in a new tab)

GETTING ACTIVE WITH PASSIVE CROSSINGS: INVESTIGATING THE EFFICACY OF IN-VEHICLE AUDITORY ALERTS FOR RAIL ROAD CROSSINGS

Landry, Steven

mtu Repository record for GETTING ACTIVE WITH PASSIVE CROSSINGS: INVESTIGATING THE EFFICACY OF IN-VEHICLE AUDITORY ALERTS FOR RAIL ROAD CROSSINGS (opens in a new tab)