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Showing 1 to 1 of 1 for “"GIST Notch KIT Sarcomas HES"”.

  1. Anti-Tumor Effects of The Notch Pathway In Gastrointestinal Stromal Tumors

    <p>Gastrointestinal Stromal Tumors (GIST) are sarcomas driven by gain-of-function mutations of <em>KIT </em>or<em> PDGFRA</em>. Although, the introduction of tyrosine kinase inhibitors has dramatically changed the history of this disease, evidences emerge that inhibition of KIT<em> </em>or PDGFRA …

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