Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 3 of 3 for “"GGCX"”.
-
The role of genetic variation in VKORC1 and GGCX on warfarin response in a South African population
… c.-1639G>A, VKORC1 c.1173C>T, VKORC1 c.3730G>A, GGCX c.1218C>T and GGCX c.1242C>T. Results: We report an association of age with warfarin dose, where, older patients had lower dose requirements (p>0.001 in MA; p>0.042 in SAB). Higher BMI was associated with increased stabilizing dose in the MA …
-
Molekulare Ursachen Vitamin K-abhängiger Gerinnungsstörungen
… wird von der Gamma-Glutamyl-Carboxylase (GGCX) katalysiert. Defekte in diesem Enzym wurden von zwei verschiedenen Arbeitsgruppen als Ursache für die erste Form der VKCFD-Erkrankung nachgewiesen. In dieser Doktorarbeit werden drei weitere, von unserer Arbeitsgruppe identifizierte Mutationen …
-
Novel clinical and etiopathogenetic findings in Pseudoxanthoma elasticum
… and was proven to be caused by mutations in the GGCX gene. Encoding the gamma-carboxylase, an enzyme important in the vitamin K (VK)-cycle, this observation implicated VK and proteins depending on this vitamin – among which are several inhibitors of mineralization – in the pathogenesis of the …