Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 55 for “"GFR"”.
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Cloning of medaka glial cell-derived neurotrophic factor (GDNF) and its receptor GFR alpha 1
… factor (GDNF) signaling through its receptor GFRI?1 plays an important role in many biological processes including cell survival, proliferation and differentiation. The aim of this project was to isolate and characterize both Gdnf and GfrI?1 from the medaka fish (Oryzias latipes). A full …
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Development of a simple HPLC-UV method for determination of GFR by serum iohexol clearance
The glomerular filtration rate (GFR) is considered the best indicator of kidney function. Iohexol, a contrast agent, is currently considered to be a reference marker since it meets all the requirements of an ideal GFR marker. The aim of this study was to develop and validate a method for iohexol …
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Statistical analysis of renal function in patients with cancer
… is reported as the glomerular filtration rate (GFR). Many clinical decisions, for example dose calculations for chemotherapy drugs, are based on a patient’s GFR. The most accurate way to determine a patient’s GFR involves costly, time-consuming, and consequently frequently unavailable methods. …
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Evaluation of iohexol clearance to estimate glomerular filtration rate in normal horses
… Estimation of the glomerular filtration rate (GFR), accepted as one of the earliest and most sensitive assessments of renal function, can be determined in horses using standard techniques such as endogenous or exogenous renal creatinine clearance. These techniques can be time consuming, …
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The Pharmacokinetics of Oxytetracycline in Dogs With Normal and Impaired Renal Function
… percentage of normal glomerular filtration rate (GFR), was estimated by ('125)I-iothalamate total body clearance. The pharmacokinetics of oxytetracycline (OTC) were compared before and after the induction of renal failure in three experiments: single intravenous dose (11 dogs), single intravenous …
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Fuel cycle options for optimized recycling of nuclear fuel
… UO2 in self-sustaining Gas-cooled Fast Reactors (GFR). Choosing one fuel cycle strategy over the others involves trade-offs that need to be quantified. The CONFU, ABR, and GFR strategies differ from each other in terms of TRU loading in the reactor, net TRU incineration, capacities of recycling …
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Evaluation of Iohexol Clearance to Estimate Glomerular Filtration Rate in Normal Horse Foals
Estimation of the glomerular filtration rate (GFR), accepted as one of the earliest and most sensitive indicators of renal dysfunction, can be determined in horses using standard techniques In adult horses and foals, renal dysfunction can occur as a secondary complication to gastrointestinal …
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Simple Tests for Assessing Kidney and Cardiovascular Function in Chromic Kidney Disease Patients (Stages 2, 3 and 4)
… measurement of glomerular filtration rate (GFR) is an important aspect of clinical decision making and forms the basis of classification for kidney function. Moreover the interpretation of risk factors for progression of CKD linked to cardiovascular disease (CVD) remains difficult, …
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Effect of Fenoldopam on Renal Function in Normal Dogs Following Nephrotomy
… (P). Baseline glomerular filtration rate (GFR), blood urea nitrogen (BUN), serum creatinine (SCr), urinalysis (UA), and urine culture were performed prior to surgery. A left bisection nephrotomy was performed via a standard midline celiotomy. Dogs in Group F received perioperative …
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The flow structure under mixed convection in a uniformly heated vertical pipe
… in the conceptual Gas-cooled Fast Reactor (GFR) currently under development, passive emergency cooling using natural circulation of a gas at an elevated pressure is being considered. Since GFR cores have high power density and low thermal inertia, relative to the high temperature gas-cooled …
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Core design and reactor physics of a breed and burn gas-cooled fast reactor
… on the design of a Gas-cooled Fast Reactor (GFR) operating in a Breed and Burnm (B&B) fuel cycle mode. B&B refers to a once-through fuel cycle where low enriched uranium (less than 5 w/o 235U in U) subcritical assemblies are loaded into the core in equilibrium, yet in-situ plutonium breeding …
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Thermal hydraulic design of a 2400 MW t̳h̳ direct supercritical CO₂-cooled fast reactor
The gas cooled fast reactor (GFR) has received new attention as one of the basic concepts selected by the Generation-IV International Forum (GIF) for further investigation. Currently, the reference GFR is a helium-cooled direct cycle plant with core outlet temperatures in the 850"C to 10000C range. …
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The Effect of Nephrotomy on Renal Function and Morphology in Normal Cats
… cats. Methods: Glomerular filtration rate (GFR), as determined by quantitative renal scintigraphy using 99mTc-DTPA, urinalysis, urine culture, and sonographic measurement of renal size were performed pre-operatively. A left or right nephrotomy (five randomly assigned cats in each group) was …
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Τα επίπεδα του αυξητικού παράγοντα των ινοβλαστών 23 (FGF23) και της πρωτεΐνης Klotho σε σχέση με την ηλικία και τη νεφρική επαναρρόφηση φωσφόρου στην παιδική ηλικία
… σωληναριακής επαναρρόφησης φωσφόρου (TmP/GFR) και να μελετήσουμε τις παραμέτρους που τυχόν επηρεάζουν τα επίπεδα FGF23 και Klotho. Μέθοδοι: Σε 159 υγιή παιδιά (82 αγόρια) με μέση ± SD ηλικία 8.78 ± 3.47 έτη μετρήθηκε ο FGF23 (τόσο ο iFGF23 όσο και ο cFGF23) και το κυκλοφορούν Klotho …
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The Effect of Withdrawal of Angiotensin II Blockers on Serum Creatinine and Potassium in Patients with Chronic Kidney Disease
… of serum creatinine, glomerular filtration rate (GFR) and serum potassium after withdrawal of RAS blockers in the current study. METHOD: We retrieved medical records of 1,154 outpatients with chronic kidney diseases (diadetic nephropathy n=574, chronic glomerulonephritis n=580) who received …
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Vascular Mechanisms of Rhabdomyolysis-induced Acute Kidney Injury
… blood flow (RBF) and glomerular filtration rate (GFR) reduction, tubular injury, and acute kidney injury (AKI). The mechanisms that underlie rhabdomyolysis-induced AKI are not fully understood but may involve the local production of vasoactive mediators in the kidney. Myoglobin stimulated …
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Severe acute renal failure at Groote Schuur Hospital
… with a reduction in glomerular filtration rate (GFR) resulting in a failure to excrete nitrogenous waste products.
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Optimized core design of a supercritical carbon dioxide-cooled fast reactor
… in nuclear power, Gas-cooled Fast Reactors (GFRs) have received increasing attention in the past decade. Motivated by the goals of the Generation-IV International Forum (GIF), a GFR cooled by supercritical carbon dioxide (S-CO2), fueled with Light Water Reactor spent fuel transuranics, and …
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Active power ancillary service provision of commercial building energy storage resources
… proposed to improve grid frequency regulation (GFR) and day-ahead (DA) electricity market clearing. The feasibility and effectiveness of the proposed control methods are evaluated using small-signal analysis, simulation case studies, and experimental verifications. An alternative power system …
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Systems Biology Study of Breast Cancer Endocrine Response and Resistance
… α (ERα) regulated and growth factor receptor (GFR) regulated signaling pathways for survival and proliferation. A mathematical model based on the signaling crosstalk between ERα and GFR was constructed. The model successfully explains several intriguing experimental findings related to bimodal …
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