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Showing 1 to 1 of 1 for “"GFP tagged HIV-1 LTR"”.
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Cell intrinsic innate immunity protein RPRD2 restricts transcription from the HIV-1 LTR in human cell lines
HIV-1 establishes latency after infection in resting CD4+ T-cells which prevents the host from clearing the virus. Highly active antiretroviral therapy effectively keeps HIV replication under control, however, the latent reservoir remains unaffected, thus therapy is never curative. The …