Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 79 for “"GDM"”.
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Pregnancy outcomes of women with Type 2 and gestational diabetes mellitus (GDM): specific focus on client engagement with health professionals, diagnosis of GDM and supplementation with omega 3 fatty acids
… (T2 DM) and gestational diabetes mellitus (GDM). Complementary to other lifestyle factors, nutrition forms the cornerstone for achieving euglycemia to reduce potential maternal and foetal risks associated with diabetes in pregnancy such as macrosomia, hypertensive disorders and preterm …
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The effect of maternal obesity/GDM and metformin intervention on maternal, placental and fetal health
… such as Gestational Diabetes Mellitus (GDM). Placental function is often affected in obese and GDM pregnancies, which affects fetal growth and development. Recent years have implicated placental extracellular vesicles (EV) in fetal-maternal communication, with their microRNA (miRNA) …
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The use of HbA1c in predicting excessive fetal growth in women at risk of gestational diabetes
Introduction Gestational diabetes mellitus (GDM) is associated with excessive fetal growth in later gestation. Traditionally, GDM is diagnosed between 26-28 weeks’ gestation. Subsequent intervention aims to reduce the risk of excessive fetal growth and its associated sequelae. Recent data suggest …
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CHARACTERIZATION OF PLACENTAL AUTOPHAGY AND BIOENERGETICS, AND MATERNAL MICRORNAS PROFILING IN OBESE PREGNANCIES AND GESTATIONAL DIABETES MELLITUS
… contributing to Gestational Diabetes Mellitus (GDM) prevalence. The altered placental function and intrauterine environment of MO and GDM are associated with adverse maternal and fetal outcomes, with short- and long-term complications. Growing evidence suggests that both MO and GDM are …
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A Naturalistic Inquiry of the Experiences of Women Diagnosed with Gestational Diabetes
… Prevention [CDC], 2022). About 50% of women with GDM go on to develop T2DM, and babies of women diagnosed with GDM also are at increased risk of developing T2DM later in life (CDC, 2022). Effective management of GDM requires women to change their health behaviors related to diet, exercise, and …
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Characterisation of the role of mitochondrial dysfunction and meta-inflammation as a shared pathogenic network in gestational diabetes mellitus
Background Gestational diabetes mellitus (GDM) is one of the most prevalent obstetric complications, with a growing incidence resulting from upward trends in global obesity and metabolic syndrome. GDM pathology is considered a state of exaggerated insulin resistance in pregnancy, mediated by …
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Gestational Diabetes Mellitus and Infant Growth and Nutrition
Background: Gestational diabetes mellitus (GDM) is a major public health problem associated with increased perinatal morbidity and later metabolic disease, both for the mother and offspring. However, the detection thresholds for GDM are widely debated. The International Association of Diabetes in …
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Genetic and immunological risk factors of gestational diabetes mellitus
Gestational diabetes mellitus (GDM) is a heterogeneous disorder that is defined as carbohydrate intolerance with onset or first recognition during pregnancy. Impaired beta-cell function and insulin resistance are the hallmarks of GDM. The overall aim of this thesis was to study the genetic and …
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Formative research for the development of an appropriate, acceptable and feasible intervention aimed at reducing type 2 diabetes risk in disadvantaged women after gestational diabetes in South Africa
Background Gestational diabetes mellitus (GDM) is one of the most common obstetric complications, affecting 18.4 million live births globally. In South Africa, the high prevalence of GDM estimated to be up to 25.8%, is driven by the high rates of obesity. Women with a history of GDM have a …
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Gestational Diabetes Mellitus- Future risk for mother and child
Gestational diabetes mellitus (GDM) occurs as a complication in 2% of all pregnancies in Sweden. Women with GDM have a substantial risk of developing type 2 diabetes later in life, but the risk of developing type 1 diabetes is also increased. GDM increases the risk for macrosomia and caesarean …
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Role of obesity and gestational diabetes mellitus status on the expression of kisspeptin, inflammatory markers and other endocrine signals, and their correlation with foetal outcomes and placental structure
… obesity and gestational diabetes mellitus (GDM) are associated with short and long-term health risks for the mother and child. The placenta produces hormones, including steroids and cytokines, that influence maternal glucose control. Current literature links kisspeptins with …
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Towards a data-driven personalised approach to gestational diabetes care
INTRODUCTION: Gestational diabetes mellitus (GDM) is high blood glucose that is first recognised during pregnancy and is one of the most common pregnancy complications. GDM is managed through lifestyle modification and may require pharmacological therapy to normalise blood glucose levels. Self …
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Investigation of the underlying, modifiable and non-modifiable risk factors for gestational diabetes among women living in Cape Town
… in life. Understanding the risk factors for GDM is important in order to come up with intervention programs. This study aimed to determine the underlying modifiable, non-modifiable and intermediate risk factors of GDM for women living in Cape Town South Africa. We also compared lifestyle …
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The genetic background of gestational diabetes mellitus
… the genetic background of gestational diabetes (GDM) and to examine how specific genes affect the development of diabetes post partum. In the DiPiS (Diabetes Prediction in Skåne) study we typed for HLA-DQB1 alleled, the transcription factor 7-like 2(TCF7L2) rs7903146, rs12255372 and rs7901695 …
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Effect of dietary omega-3 supplementation on plasma phospholipids, neutral lipids fatty acids and antioxidant status of pregnant women with gestational diabetes and their neonates
Background: Gestational diabetes mellitus (GDM) has adverse effects on the level of docosahexaenoic acid (DHA) in phospholipids of maternal and cord red blood cells and cord plasma. This finding was of major concern because DHA is vital for maternal wellbeing and health, and for optimal development …
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Dépistage précoce du diabète gestationnel
… the prevalence of gestational diabetes mellitus (GDM) warrant the importance of screening as early as possible in order to possibly prevent short and long-term complications in both the mother and fetus. GDM screening is recommended at 24-28 weeks of pregnancy, using a 50g glucose challenge test …
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Third Trimester Plasma Metabolites Associated with Gestational Diabetes: An Ancillary Analysis of the Healthy Beginnings Trial
… </strong>Gestational Diabetes Mellitus (GDM) results in complications affecting both mother and child. The implementation of metabolomics to assess metabolite alterations is needed to better understand its etiology. Prior research by our lab in first trimester samples of GDM patients …
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An Evaluation of Diagnostic Approaches for Gestational Diabetes Screening in South Africa
Background: Gestational diabetes mellitus (GDM) poses substantial risks to both mothers and their offspring. In South Africa, screening practices vary, and pregnant women are not screened universally due to resource constraints. This study investigates the implications of using point of-care (POC) …
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Gestational Diabetes: the Role of Prenatal Care On Excessive Fetal Growth Outcomes and Postpartum Screening For Diabetes Among South Carolina Women (2004-2007)
<p>Gestational Diabetes Mellitus (GDM) is a complicated medical condition that can have a tremendous impact on infant and maternal health. This study examined aspects of both prenatal and postnatal care for women with GDM. Study one focused on examining the impact of prenatal care on LGA/Macrosomia …
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Early Manifestation of Cardiovascular Disease Risk Factors in Offspring of Mothers with Previous History of Gestational Diabetes Mellitus
… of maternal gestational diabetes mellitus (GDM) on cardiovascular disease (CVD) risk factors in offspring. Subjects and Methods: A total of 298 offspring (202 offspring of GDM mothers and 96 offspring of mothers with impaired glucose tolerance [IGT]) participated in the study. CVD risk …
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