Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 7 of 7 for “"GDF-15"”.
-
Neue Biomarker und Multimarkerstrategien für eine optimierte Risikostratifizierung von Patienten mit Lungenembolie
… (H-FABP) und growth-differentiation factor-15 (GDF-15) für die Risikostratifizierung von Patienten mit akuter Lungenembolie untersucht. In einem Patientenkollektiv von 107 Patienten erwies sich H-FABP als zuverlässiger prognostischer Parameter für das Auftreten von Lungenembolie-assoziierten …
-
The effects of metformin on the gastrointestinal tract
… into metformin action in intestinal cells. GDF-15 is a stress activated hormone that acts on its cognate receptor GFRAL expressed almost exclusively in the brainstem to elicit an inhibition of food intake. GDF-15 was one of the serum biomarkers identified in T2DM patients associated with …
-
Characterisation of cardiac remodeling associated with pregnancy: providing insights to peripartum cardiomyopathy
… the circulatory level of growth differentiation 15 (GDF-15) in PPCM patients and matched healthy controls. Results: Cardiac structural, functional and morphological changes were observed in mice and all the parameters were resolved postpartum. Strikingly, volume load, cardiac hypertrophy and …
-
ULTRA-LOW LEVEL SOLUBLE P24 IS ASSOCIATED WITH INFLAMMATION IN PEOPLE WITH HIV ON LONG-TERM VIROLOGICALLY SUPPRESSIVE ANTIRETROVIRAL THERAPY
… TNF-α, IL-17A, IL-8, sCD14, sCD163, TIMP-1, and GDF-15 compared to controls. Several biomarkers were associated with the VACS Index 2.0 in univariable analyses, but only IP-10 and GDF-15 remained independently associated in multivariable modelling. Soluble p24 was detectable in 25/120 (20.8%) PWH …
-
Role of the systemic inflammatory response in the clinical and biological features of incurable cancer and cachexia
… score (37.6/100). In terms of cytokine analysis GDF-15 (r=0.511, p=0.004) and IL-1ra (r=0.492, p=0.002) had a significant relationship with BMI. There was a strong correlation between IL-6 levels and constipation (r=0.663, p=<0.01) and a moderate correlation between IL-8 levels and nausea and …
-
The Effects of Induced Polycystic Ovary Syndrome in NAG-1 Transgenic Mice
<p>Polycystic ovary syndrome (PCOS) is the leading cause of infertility among women in the US and the most common endocrine disorder among women. PCOS is characterized by cystic ovaries, hyperandrogenism (heightened levels of male sex hormones), altered menstrual cycles and various metabolic …
-
THE ROLE OF EXTRACELLULAR VESICLES IN HEART DISEASES
… levels of NT-proBNP, vWF, tPA, SPD, CD163, and GDF-15 (p < 0.05–0.0001), clustering within hemostasis and fibrinolytic networks. Collectively, these findings suggest that circulating EVs in HCM carry molecular signatures consistent with myocardial remodeling, endothelial activation, and …