Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 62 for “"GAPDH"”.
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Investigating the Role of RAP2.12 and GAPDH in Photosynthetic CO2 Fixation to Improve Drought Tolerance
… has been revealed that the relative amounts of GAPDH plastids subunit (A2B2) and (A4) vary between species, but almost always the A2B2 form is predominant (Howard et al., 2011b). Previously, plants without A4 have been recognised, but no plants without A2B2 have been identified. The second …
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The Study of Glyceraldehyde -3 -Phosphate Dehydrogenase (Gapdh) Function Targeted by Estrogen and Progesterone in the Central Nervous System: Physiological Implications
… model for the membrane action of estradiol on GAPDH in the hippocampus that reflects recent interesting reports from other laboratories as well as my own contributions to these novel functions of GAPDH.
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GLYCERALDEHYDE 3-PHOSPHATE DEHYDROGENASE: A NEW MOLECULAR TARGET IN CHEMOTHERAPY
… cycle. Glyceraldehyde 3-phosphate dehydrogenase (GAPDH) occupies a central position in the glycolytic pathway thus playing a critical role in the energy metabolism of cancer cells. Along with its enzymatic activity, GAPDH is a multifunctional protein which acts as a signaling and regulatory …
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Tyrosine nitration and altered protein pool levels of glyceraldehyde-3-phosphate dehydrogenase following ischemia/reperfusion: The influence of aging in glycolytic skeletal muscle
… oxidative damage\r\nexperienced by the muscle. GAPDH protein levels were measured by Western blotting.\r\nWe observed that the enzyme is significantly decreased at 3 and 5 days of reperfusion in\r\nthe young muscle, while the enzyme was significantly decreased in the aged muscle at 1,\r\n3, 5, …
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Physiological and Biochemical Response of Saccharomyces cerevisiae to Desiccation and Rehydration
… on glyceraldehyde-3-phosphate dehydrogenase (GAPDH, E.C. 1.2.1.13), a multifunctional protein that is involved in several cellular processes other than glycolysis, including nuclear translocation under stress and intracellular sensing of oxidative stress during apoptosis. Here, GAPDH was …
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Prävention des Ischämie-Reperfusionsschadens in der Leber
… von Glyceraldehyd-3-phosphat-dehydrogenase (GAPDH), einem Schlüsselenzym der Glykolyse, beim IRS genauer betrachtet. Hormonelle Präkonditionierung mit dem Atrialen Natriuretischen Peptid (ANP) verringerte die RNA-Bindungsaktivität von IRP-1. Dieser Effekt wird wahrscheinlich über cGMP …
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A Study of the Effects of Polyethylene Glycol on Interactions Between Glycolytic Enzymes and F-Actin, and Among Glycolytic Enzymes
… oxidoreductase (GAPDH, EC 5.3.1.1), D-glucose-6-phosphate ketol-isomerase (GPI, EC 5.3.1.9), (S)-lactate:NAD+ oxidoreductase (LDH, EC 1.1.1.27), and ATP:Pyruvate O$\sp2$-phosphotransferase (PK, EC 2.7.1.40) with each other, with ATP:D-fructose-6-phosphate …
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Mechanisms of monohalogenated acetic acid induced genomic DNA damage
… DNA. Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) was investigated as a possible molecular target for the monoHAAs; each of the monoHAAs inhibited GAPDH with variable efficacy. The ability to inhibit GAPDH correlated strongly with multiple toxicological endpoints measured for the monoHAAs. …
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Junction Specificity and Transmembrane Linkages of Integrins
… proteins identified the 36 kD protein as GAPDH. The other 2 protein bands were heterogeneous, containing proteins found in the synaptic vesicle fusion core complex. Immunolocalization of P4B2 antigen in developing cultured muscle cells showed that the antigen is incorporated into Z-lines …
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Toxicity mechanism of anthropogenic water contaminants: drinking water disinfection by-products (haloacetic acids) and particle associated contaminants from sealcoats (polyaromatic hydrocarbons) in lake sediments
… of glyceraldehyde-3-phosphate dehydrogenase (GAPDH) where, di-, and triHAAs were weaker inhibitors. MonoHAAs greatly reduced the ATP contents of the cells. Unlike monoHAAs, triHAAs increased the cellular ATP levels as compared to the negative controls. Exogenous pyruvate supplementation …
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Effects of heat shock, hypoxia, post-mortem interval and glioma disease state on heat shock gene HSPA expression
… showed a marked increase in HSPA expression. GAPDH was used as a control gene for these studies, and exhibited a consistent level of expression in normal and tumourous cell lines and tissue samples under normal and hypoxic conditions, and also in post mortem tissues exposed to heat shock. For …
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Gene expression of DNA repair proteins in colorectal cancer and medulloblastoma
… and glyceraldehyde 3-phosphate dehydrogenase (Gapdh) as the standard. Of the matched samples investigated, 75% showed increased expression of one or more of the DNA repair genes analysed, however, there was no clear pattern of expression and a wide range of expression levels observed for …
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Interaction between respiratory carbon flow and photosynthetic light harvesting in the green alga, selenastrum minutum
… conversion indicated that carbon flow, via NAD-GAPDH and PGA kinase, was significantly enhanced by class 1 treatments while no significant change was noted for class 2 treatments. NAD-GAPDH has been shown to be 86% localized in the chloroplast in Chlamydomonas reinhardtii (Klein, 1986 Planta …
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The electrophysiological and molecular effects of chronic beta-adrenoceptor antagonist therapy on human atrium
… a marker of total RNA, and the housekeeping gene GAPDH. The levels of mRNA for the accessory subunits KChIP2, KChAP, Kvβ1 and 2 and Frequenin, which modify Kv4.3 expression and function, were also measured. No change was found in the relative mRNA levels of any of these ion channel subunits in …
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Molecular characterization and promoter analysis of the maize cytosolic glyceraldehyde 3-phosphate dehydrogenase gene family
… glyceraldehyde-3-phosphate dehydrogenase (GAPDH) has been identified as one of the anaerobic polypeptides and mRNAs corresponding to a member of the gpc multi-gene family, gpc3, increase under anaerobiosis. This study extends further analysis of the gpc gene family, with specific emphasis …
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Investigating the role of circulating cell-free dna as a mechanistic biomarker in inflammatory bowel disease: development of an integrated precision-medicine enabled platform in Scotland
… chain reaction (dPCR) for COX3, ND2 and GAPDH genes, fragment analysis with the Agilent BioAnalyzer, and cfDNA sequencing using both Nanopore and Illumina platforms. RESULTS: Patients with highly active IBD (requiring admission to hospital) had significantly higher total cfDNA (median …
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Avaliação dos fatores de risco para o câncer de mama e dosagem de frações livres de DNA em mulheres atendidas na Maternidade Odete Valadares, em Belo Horizonte, Minas Gerais
… o gliceraldeído-3- fosfato desidrogenase (GAPDH) e β-actina. Foram verificados maiores níveis de FLDNA em pacientes com Ca mama utilizando a β-actina em relação aos controles, e o GAPDH mostrou-se incapaz de identificar positivamente as pacientes portadoras de neoplasia. Os resultados …
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Protein glycosylation by NleB and the secretion of therapeutic nanobody fusions
… glyceraldehyde 3-phosphate dehydrogenase (GAPDH), and tumor necrosis factor receptor type 1-associated death domain protein (TRADD), were then studied. Results detected that all three mammalian substrates were glycosylated by NleB on arginine residues R177, R197/R200, and R235, …
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Effect of laminar shear stress on gene regulation, protein synthesis, and protein secretion by cultured human endothelial cells
… gene, glyceraldehyde 3-phosphate dehydrogenase (GAPDH) was found to be the same in control and sheared cells. The fact that GAPDH was unregulated indicates selectively in cellular response to shear stress in addition to validating the PCR technique. Endothelin (ET), a 21-amino acid peptide …
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Characterization of Alternaria alternata isolates causing brown spot of potatoes in South Africa
… confirmed by molecular phylogeny using the GAPDH, EF1α and a combined phylogeny of these gene regions. All isolates formed one section with A. alternata. The isolates also grouped together with A. arborescens, A. tenuissima, A. longipes and A. gaisen, which were all recently characterized …
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