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Showing 1 to 4 of 4 for “"GABOXADOL"”.
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The Role of Sleep in Memory Consolidation with an Induced Sleep-Like State in Drosophila AND The Role of Alpha-synuclein in Fatty Acid Metabolism
… the memory consolidation process.</p><p>Results: Gaboxadol, an extra-synaptic GABAA receptor agonist, induced a sleep-like state that meets all the behavioral criteria of a spontaneous sleep-like state in flies. The induced sleep-like state following Gaboxadol treatment facilitated the formation …
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Investigating the role of extrasynaptic GABAA receptors located in the infralimbic cortex in the binge-like alcohol intake of male C57BL/6J mice
… in rodents using the δ-subunit selective agonist Gaboxadol (THIP) have found both promotional and inhibitory effects on alcohol consumption. The goal of this project was to determine the role of extrasynaptic GABAA receptors located in the infralimbic cortex (ILC) in the binge-like alcohol intake …
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Exploiting the Power of Sleep to Rescue Long-Term Memory Defects in a Drosophila Memory Mutant
… shown that pharmacological sleep induction with gaboxadol both prior to and following training can restore courtship long-term memory in the Drosophila memory mutant rutabaga. To identify the sleep-related center responsible for long-term memory restoration, we employed CsChrimson optogenetic …
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Unique Response Properties and GABA<sub>A</sub> Receptor Function in Medial Geniculate Body Neurons of Young and Aged Fischer Brown Norway Rats
… function were examined. Low concentrations of gaboxadol (GABA<sub>A</sub>R agonist) activated a gabazine-sensitive (GABA<sub>A</sub>R antagonist) tonic current, providing support for the expression of functional high affinity GABA<sub>A</sub>Rs in the MGB. Activation of high affinity …