Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"GABAARγ2"”.
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Nova Regulation of Alternative Splicing in the CNS
… inhibitory neurotransmitter receptor subunit, GABAARγ2, and the alternatively spliced exon H in Nova-1's own message. Nova acts to enhance alternative exon inclusion in GlyRα2 and GABAARγ2 mRNAs and to repress alternative exon usage in its own message, thus acting as a dual function splicing …
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Molecular Pathogenesis of Spinocerebellar Ataxia type 10
… We clearly showed that aberrant splicing of GABAARγ2 and GlyRα2 causes disruption of inhibitory transmission in Purkinje cells in the SCA10 cerebellum. We demonstrated that abnormal electrophysiology in SCA10 occurs specifically through modulating GABA neurotransmission but not glycine. In …
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Molecular Pathogenesis of Spinocerebellar Ataxia type 10
… We clearly show that aberrant splicing of GABAARγ2 and GlyRα2 causes disruption of inhibitory transmission in Purkinje cells in SCA10 cerebellum. We demonstrate that abnormal electrophysiology in SCA10 occurs specifically through modulating GABA neurotransmission but not glycine. In our …