Global ETD Search
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Showing 1 to 2 of 2 for “"G93A-Mutation"”.
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Recombinant DDX58 associates with SOD1 protein and selective miRNA changes in secreted EVs
… We showed DDX58 local interactions with wt and G93A mutant SOD1 proteins, but not with TDP-43. By processing the cell secretome with orthogonal approaches for EV isolation, we found that DDX58 is included as EV cargo and influences SOD1 protein EV-enrichment. Interestingly, we observed that an …
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Über die Auswirkungen systemischer bakterieller Begleitinfektionen bei Amyotropher Lateralsklerose
… vermuteten Mechanismen an ALS-typischen humanen G93A-transfizierten Neuroblastomzellen (Linie SH-SY5Y) und G93A-transgenen ALS-Mäusen untersucht. Es konnte gezeigt werden, dass die ALS-typischen Zellen empfindlicher auf das vom Bakterium Streptococcus Pneumonia freigesetzte Toxin Pneumolysin und …