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Showing 1 to 5 of 5 for “"G4LZI3"”.
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Structural Determination of the novel Universal Stress Protein G4LZI3 from Shistosoma mansoni using X-ray Crystallography
… of the novel Universal Stress Protein G4LZI3 from Schistosoma mansoni using X-ray Crystallography Priscilla Masamba PhD (Biochemistry) thesis, Department of Biochemistry and Microbiology, Faculty of Science and Agriculture, University of Zululand Schistosoma mansoni is a parasitic …
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Molecular cloning, recombinant protein expression and structural characterization of a universal stress G4LZI3 protein from Schistosoma mansoni
… Schistosoma mansoni universal stress protein G4LZI3, which has been hypothesized as a druggable target, as well as a vaccine candidate against the parasite in humans. Bioinformatics analysis of the G4LZI3 gene sequence was done to predict structural information about the protein which served …
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Structural Characterization of the interaction between divalent cations and the novel Schistosoma mansoni Universal Stress Protein G4LZI3
… Universal Stress Proteins and focused on a novel G4LZI3 USP, which has been put forward as a possible candidate vaccine. A sufficient amount (0.518mg/ml) of recombinant G4LZI3 protein was successfully expressed using 0.5mM IPTG and subjected to a Nickel-NTA column for purification. The fractions …
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Biophysical Characterization of the Interaction between the Universal Stress G4LZI3 protein and Schistosoma mansoni Hsp60 Substrate Binding Domain
… the interaction between the S.mansoni G4LZI3 protein and the S.mansoni Hsp60, this requires understanding the structure of the two proteins and their preferred orientation upon interaction. Employment of various bioinformatics tools in this study helped in bringing insight on the …
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Biophysical characterisation of the interaction between the S.mansoni G4LZI3 protein and the NAD binding domain of glyceraldehyde-3 phosphate dehydrogenase
… between two Schistosoma mansoni proteins, G4LZI3 and the NAD binding domain of G3PDH, that are crucial for protection and energy generation of the worm post intra-mammalian invasion. Prior to the in vitro studies, numerous bioinformatics studies were done in order to obtain and examine the …