Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 4 of 4 for “"G3BP"”.
-
The Interaction Between Host G3BP and Viral Nucleocapsid Protein Regulates SARS-CoV-2 Replication
<p>G3BP1/2 are RNA-binding proteins that promote condensation to form stress granules in response to various cellular stresses, including viral infection. G3BP1/2 are prominent interactors of the nucleocapsid (N) protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). However, the …
-
Translational Repression of G3BP in Cancer and Germ Cells Suppresses Stress Granules and Enhances Stress Tolerance
… translational inhibition of the key SG nucleator G3BP. MAGE-B2 reduces G3BP protein levels below the critical concentration for phase separation and suppresses SG initiation. Importantly, knockout of the MAGE-B2 mouse ortholog or overexpression of G3BP1 confers hypersensitivity of the male …
-
Ruolo della TDP-43 nella formazione dei granuli da stress nella Sclerosi Laterale Amiotrofica
… compare with healthy controls. Expression of G3BP, a core stress granule component, was significantly lower after sodium arsenite treatment in fibroblasts from patients carriying TARDBPA382T mutation compare with healthy controls. We can conclude that TARDBPA382T mutation caused a reduction in …
-
Regulation of cellular growth and identification of stromal gene signatures in breast cancer
… in heat shock, but not arsenite, treated cells. G3BP proteins are well-known stress inducers and we identified a direct interaction between PKCα and the G3BP2 isoform. G3BP2 belongs to a family of three homologous proteins with RNA-regulating capacities. With the aim to identify specific RNA …