Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 91 for “"G0"”.
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Strange quark contributions to nucleon electric and magnetic form factors from parity-violating electron scattering asymmetries in the backward angle g0 experiment
The G0 collaboration has measured parity-violating asymmetries in elastic electron-proton and quasi-elastic electron-deuteron scattering at Q^2 = 0.22, 0.63 GeV^2. These asymmetries are sensitive to strange quark contributions to electric and magnetic properties of the nucleon, as well as to the …
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Cell Cycle Regulation by Post-Translational and Post-Transcriptional Mechanisms in an Anaerobic Extremist- the Anoxia Tolerant Turtle, Trachemys Scripta Elegans
… and ATR/Chk2) that are known to regulate G1/G0 phases of the cell cycle. Importantly, there is extensive regulation of Cyclin D1 protein by (1) Akt/GSK-3β signaling, (2) post-translational modification, (3) an AU-rich region, and (4) microRNA-induced translational suppression. This study also …
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Regulatory Balance Between the Peptide Trasporter, Pept1, and Amino Acid Transporter Gene Expression in the Enterocyte
… cPepT1 shRNA or control shRNA expressing G0 chickens were generated by embryo injection of pseudolentiviral particles followed by ex ovo egg culture. Overall, 9 potential G0 cPepT1 overexpressing chickens, 15 potential G0 cPepT1 shRNA expressing chickens, and 4 potential G0 control shRNA …
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Validierung der Zellzyklusdiagnostik bei Ataxia telangiectasia
… den Anteil der nicht-proliferierenden Zellen (G0,G1) sowie den Anteil der in der G2-Phase des 1. Zellzyklus verbleibenden Zellen bezogen auf die Wachstumsfraktion (G2/GF). Der Anteil der nicht-proliferierenden Zellen (G0,G1) ist ein Maß für die Stimulierbarkeit der Lymphozyten. Diese …
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Novel Approaches to Transgenesis in the Teleost Medaka (Oryzias latipes)
… promoter-dependent transgene expression in G0, indicating that SB IR/DRs significantly enhance transient transgene expression. G0 expression was a reliable indicator for the efficient selection of transgenic founders. Embryos that exhibit a uniform GFP expression in G0 result in the highest …
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The use of foil generated vorticity as a hover actuator system for undersea vehicles
… provide the highest thrust coefficient of 3.1 at G0=600, hdc= 1.5, and f=0.4Hz for the treading water mode. Significantly lower thrust coefficients are observed for the figure eight mode with maximum of 1.8 occurring at G0=300, hdc=1, and f-0.2Hz. In addition to finding the optimal regime of …
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Activation of the p53 pathway in combination with photon irradiation for the treatment of neurological tumour cells
… AMG232 induced a stronger and more sustained G0/G1 arrest in TP53-wild-type cells, supporting activation of the canonical p53–p21 axis. TP53-mutant cells displayed only partial or transient G0/G1 accumulation, suggesting the involvement of p53-independent stress responses rather than effective …
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Caracterização estrutural, dinâmica e reológica de suspensões coloidais via simulação molecular
… coefficient and viscosity) and rheological (G0 and G00 ) properties under different conditions. The validation and tests of these algorithms are made by comparing with literature results of a LennardJones fluid under different conditions. The methods are used to calculate structural and …
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Ruolo dell'Enantiomero (R)-9-HSA nel controllo della proliferazione in una linea di Adenocarcinoma del Colon umano
… cell line, induced a proliferative arrest in G0/G1 phase mediated by a direct activation of the p21WAF1 gene, bypassing p53. We have previously shown that 9-HSA controls cell growth and differentiation by inhibiting histone deacetylase 1 (HDAC1) activity, showing interesting features as a new …
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Synthese und in vitro Wirksamkeit von linear-dendritischen und linearen Polymer-Wirkstoff-Konjugaten von Doxorubicin und Paclitaxel auf der Basis von Poly(ethylenglykol)
… Die mPEG(5000)-dendr-PLL-Doxorubicin-Konjugate G0 bis G3 zeigten in vitro Wirksamkeit in 2 Tumorzellinien. Eine generationsabhängige antiproliferative Aktivität wurde zwischen den Konjugaten von G0 und G1 beobachtet: hier nahm die Aktivität um das Doppelte zu. Die IC50-Werte der übrigen …
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Renal Risk Variants of Apolipoprotein L-1 Form Channels at the Plasma Membrane that Lead to a Cytotoxic Influx of Calcium
… overexpression of G1 and G2, but not wild-type G0, leads to swelling and eventual lysis. However, the mechanism of cell death remains elusive with multiple pathways being invoked, such as autophagic cell death mediated by a BH3 domain in APOL1, which we evaluated in this study. We hypothesized …
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ASSESSING THE ROLE OF EXTERNAL PHOTOEVAPORATION OF PROTOPLANETARY DISCS IN NEARBY STAR-FORMING REGIONS
… their lifetime even under weak FUV fields (<1000 G0), where no direct observational evidence of ongoing photoevaporation (i.e., proplyds) is currently available. I demonstrate that external photoevaporation must be included alongside with viscous evolution to explain the gas sizes and masses of …
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Coordination of origin licensing and cell cycle entry
… yeast retain a subset of pre-RCs at origins in G0. Although these origins are sufficient to duplicate the genome, additional pre-RCs are normally assembled as cells exit G0 and use of these additional licensed origins increases viability. Finally, this additional licensing is monitored by a …
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Beyond the tanh method-looking for explicit travelling wave solutions to partial differential equations
… that popular methods such as the tanh-method, G0/G-method and many more are special cases of the presented approach. Analytical solutions to several examples of nonlinear equations are illustrated. In the application, we use the Maple program to compute solutions to nonlinear systems of …
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On two problems related to the Laplace operator
… the class of rearrangements of a fixed function g0 defined on a smooth and bounded domain Ω in Rn. We prove existence and uniqueness results, and in special cases, we prove results of symmetry and results of symmetry breaking for the minimizer.
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The Role of SOX2 in Colon Cancer Progression
… with increased proportion of cancer cells in G0-G1 phase of cell cycle. Changing SOX2 protein levels in cells had a direct correlation with mRNA levels of RBL2-HUMAN and CDKN2B genes, which serve as regulators of G0 and G1 respectively. SOX2 was shown to physically bind and to the promoter …
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Perillyl alcohol and perillic acid enhanced the sensitivity of head and neck cancer cells to radiation treatment in vitro
… respectively. PA induced cell-cycle arrest in G0/G1 phase, caused cell death via apoptosis and a reduction in p53 protein in SCC-25 cells.
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Development and application of a high throughput cell based assay to identify novel modulators of ERK1/2 activation and,Functional characterisation of the candidate Radial spokehead like (Rshl1)
… finding that over-expression of Rshl1 caused a G0/G1 phase arrest in human kidney cells via an up-regulation of p57KIP2 expression and stabilization of ERK3. Rshl1 thus regulates the cell cycle by inhibiting the ERK1/2 kinase. It interacts with critical signalling proteins in the cell and …
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Imbalance Between Neutrophil Elastase and Elafin Promotes Breast Cancer Growth and Progression
… a model system. Elafin was highly expressed in G0-arrested HMECs, suggesting a previously unrecognized role for elafin in growth control. Stable knockdown (KD) of elafin compromised the ability of HMECs to maintain G0-arrest during long-term growth factor deprivation. This effect was reversed by …
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Funktionelle Charakterisierung der humanen Polo-Kinase Plk2/Snk im Zell- und Centrosomenzyklus
… wurde die Aktivität in humanen Fibroblasten am G0/S-Übergang untersucht. Es konnte gezeigt werden, dass Plk2 bereits nach dem Wiedereintritt in den Zellzyklus aktiviert wird und die Aktivität in der Mitte der G1-Phase wieder absinkt. Diese Ergebnisse deuten auf eine Funktion von Plk2 am …
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