Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"G protein-coupled estrogen receptor 1"”.
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G-Protein-Coupled Estrogen Receptor-1 (GPER): A Potential Target For Xenoestrogens During Vertebrate Embryogenesis.
<p>G-protein-coupled estrogen receptor 1 (GPER) is a G-protein-coupled receptor that induces non-genomic signaling in response to some nuclear estrogen receptor ligands. To date, the distribution and functional characterization of GPER within vertebrate organs have been restricted to juvenile and …
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The Non-genomic Signaling Pathways Mediated By G-protein Coupled Estrogen Receptor 1 (GPER) In Coronary Arteries
… A promising new avenue of study is the novel G protein-coupled estrogen receptor (GPER) which mediates estrogen action. The major purpose of my studies in this dissertation is to investigate the role of GPER in porcine coronary artery tone regulation. In a series of studies, we tested four …
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G protein-coupled receptor regulation: The role of protein interactions and receptor trafficking
The superfamily of G protein-coupled receptors (GPCR) is the largest gene family in the human genome. GPCR-mediated signaling operates in every human cell, and about 50% of existing clinically useful drugs act through GPCR. Kinins are proinflammatory peptides that are rapidly produced …
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Sex Specific Gene Expression Profiles In Fibrosis and Copd
… We hypothesize that the expression of steroid receptors and metabolizing enzymes will differ by gender and disease. To elucidate immune and extracellular matrix remodeling (ECM)- and hormonally-related genes that are differentially expressed by gender in human control and diseased lung tissues …
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Viral- and host-targeted interventions to improve influenza disease outcomes
… parasite, must coopt a myriad of host cell proteins and processes in order to complete its lifecycle, and produce infectious progeny virions in hopes of spreading to and infecting new cells and hosts. At the same time, the infected host must both detect this viral invader, as well as mount …