Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 8 of 8 for “"Fungal pathogenesis"”.
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Molecular dissection of Alternaria brassicicola pathogenesis mechanisms
Alternaria brassicicola is a necrotrophic fungal pathogen that causes black spot disease on cruciferous plants including economically important Brassica species and the model plant Arabidopsis thaliana. The purpose of this dissertation was to gain a better understanding of the pathogenesis …
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Cellular Copper Import Mechanisms via Secreted Cuproproteins: Exploring Metal Homeostasis in Pseudogymnoascus destructans
… investigates the metal stress response of the fungal pathogen Pseudogymnoascus destructans (Pd), which causes White-Nose Syndrome in bats. Special emphasis is placed on understanding how cellular metal status effects Bim1-like Proteins (BLPs) and high-affinity copper transporters (CTR proteins) …
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Identification and characterization of Fusarium graminearum pathogenesis genes and determination of aggressiveness
… F. graminearum, yet little is known about other pathogenesis compounds or pathways used by the pathogen to infect wheat. To identify essential fungal pathogenesis genes and determine whether host resistance impacts aggressiveness of a given isolate, a paired strategy of isolate and transcriptome …
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Identification of up-regulated genes of the hyphomycete, Beauveria bassiana, during infection of Leptinotarsa decemlineata
… step in our understanding of the mechanisms of fungal pathogenesis in insect, which could further allow the production of more efficient mycoinsecticides and contribute to reductions in chemical pesticides use.
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Sexual Reproduction and Signal Transduction in the Candida Species Complex
… Despite increases in drug resistance, the antifungal armamentarium has changed little over the past decade. Thus increasing our understanding of the life cycles of these organisms, not only how they propagate themselves, but also how genetic diversity is created within the population is of …
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Tor Signaling in the Fungal Kingdom
<p>Fungal cells sense the amount and quality of external nutrients through multiple interconnected signaling networks, which allow them to adjust their metabolism, transcriptional profiles and developmental programs to adapt readily and appropriately to changing nutritional states. In organisms …
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Investigation of Novel Virulence Mechanisms In Candida Albicans
… albicans </em>is the most important fungal species associated with humans. Normally present in the human microbiome as a commensal colonizer, <em>C. albicans </em>is also the fourth most prevalent organism isolated from bloodstream infections in hospitals. Disseminated infections have …
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Alternative Carbon Utilization As A Virulence Determinant For Candida Albicans
… which has a mortality rate reaching 50%. As antifungal resistance continues to rise, it is critical that I understand the molecular basis of disseminated fungal infections.</p> <p>The phagocytes of the immune system are especially important for preventing disseminated infection. Macrophages are …