Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 114 for “"Functional MRI"”.
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A generative model for activations in functional MRI
Detection of brain activity and selectivity using functional magnetic resonance imaging (fMRI) provides unique insight into the underlying functional properties of the brain. We propose a generative model that jointly explains neural activation and temporal activity in an fMRI experiment. We derive …
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Expanding the role of functional mri in rehabilitation research
Functional magnetic resonance imaging (fMRI) based on blood oxygenation level dependent (BOLD) contrast has become a universal methodology in functional neuroimaging. However, the BOLD signal consists of a mix of physiological parameters and has relatively poor reproducibility. As fMRI becomes a …
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Functional MRI in the presence of repetitive, sub-concussive impacts
… impacts is not well understood. This study uses functional MRI measurements of high school football players to identify functional changes, even in the absence of clinical symptoms.</p>
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Pattern codes for perceived gaze direction revealed by functional MRI
… similar gaze representations in humans using fMRI have provided mixed results. This thesis describes research where multivariate pattern analysis (MVPA) methods are applied to fMRI data in order to better explain how the human brain and particularly STS codes perceived gaze direction. After …
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Alterations in brain connectivity after spinal cord injury using functional MRI
… that can be used to characterize SCI. Altered functional connectivity in the brain has been observed in a number of neurological patient populations. Hence, it was hypothesized that such alterations in brain connectivity occurs after SCI as well. In this study, functional magnetic resonance …
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Improving Data Quality for High Resolution Functional MRI in Cognitive Neuroscience Applications
… the first successful Magnetic Resonance Imaging (MRI) image was produced by Paul Lauterbur in 1973, the field of MRI has been improving by leaps and bounds. The number of MRI and functional MRI (fMRI) papers have sky rocketed over the last decade, alongside with advancements in MRI field strength …
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Quantitative comparison of functional MRI and electro-cortical stimulation for function mapping
Mappinlg functional areas of the brain is of vital importance for plallnning tumor resectiol. A accurate mapping provides information to leurosurgeons about which areas of the brain are eloquent, and should be avoided while removinlg the tumor. With the recent increase in the use of functional MRI …
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Cerebral hemodynamics and oxidative metabolism dynamics observed by calibration of functional MRI
Thesis (Ph. D.)--Massachusetts Institute of Technology, Whitaker College of Health Sciences and Technology, 1998.
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A functional MRI study of the distributed neural circuitry of learning and reward
… established for each of the responsive subjects. Functional magnetic resonance imaging (fMRI) with blood oxygenation level dependent (BOLD) contrast was then used to evaluate the brain activation in response to behaviorally characterized electrical stimuli. High resolution anatomical images …
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Functional MRI Activation of Inhibitory Control in Adolescents and Young Adults with Multiple Sclerosis
… functions. This study examined the concept of functional reorganization concerning inhibitory control using a simple Go/No-go (GNG) functional MRI paradigm in pediatric-onset MS. The control group demonstrated greater functional activation as compared with the patient group in several regions: …
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Self-navigated prospective motion correction of repeated 3D-EPI acquisitions for functional MRI applications
Functional magnetic resonance imaging (fMRI) typically employs one of the fastest pulse sequences – known as echo-planar imaging (EPI) – to repeatedly image the whole brain as stacks of two-dimensional slices. Two-dimensional EPI (2D-EPI) is preferred over threedimensional (3D)-EPI as it is more …
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Insights into brain networks from functional MRI and graph analysis during and following attentional demand
… of task performance. Data basis were functional MRI data which were analyzed with a BOLD approach and graph analysis. Brain networks that mediate ‘attentional effort’ were identified as being involved during the task. These networks were further functionally differentiated in …
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Cognitive therapy, working memory training, and the treatment of Methamphetamine Use Disorder - a functional MRI study
… and the n-back working memory task adapted for fMRI were measured and compared pre- and post- intervention. No significant differences were present between groups prior treatment on behavioural measures, demographic measures, and fMRI activity. The brief cognitive therapy appeared to reduce …
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Functional MRI Investigation of the Neural Basis of Human Pain Processing in the Brainstem and Spinal Cord; Descending Regulation and Chronic Pain
Pain is a complex experience that includes sensory components, descending pain modulation, and cognitive and emotional effects. A combination of any or all of these effects may be altered in chronic pain conditions. The objective of this thesis was to investigate how network connectivity is altered …
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Vascular Reactivity by Blood Oxygen Level Dependent Functional MRI in Cerebral Amyloid Angiopathy: Comparison with Alzheimer's Disease and Assessment of Longitudinal Change
… (BOLD) signal amplitude in response to a visual fMRI task has recently been implicated as a surrogate marker for impaired vascular reactivity in CAA. There have been no studies investigating how the BOLD amplitude changes in other Aβ diseases that present with CAA (Alzheimer’s disease (AD) or mild …
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fMRI assessment of ischemic stroke in humans
… The main goal of this study is that the functional MRI data can be used to obtain both structural and functional information about lesions in stroke patients. It was hypothesized that the lack of oxygen supply might be directly caused by lower level rate of blood flow, which can be traced …
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The BOLD MRI response of the brain to alterations in arterial blood pressure
… level dependent magnetic resonance imaging (BOLD MRI) – functional MRI. The aim of this project is to investigate the effect of dynamic blood pressure stimuli on the BOLD MRI signal in the brain. Two blood pressure stimuli were employed; thigh cuff deflation and the Valsalva manoeuvre. BOLD MRI …
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Brain Activation and Connectivity In Non-Disabled Multiple Sclerosis Patients
… tissue damage on magnetic resonance imaging (MRI). The current studies combined functional MRI and diffusion tensor imaging (DTI) to elucidate brain mechanisms associated with lack of clinical disability in patients with MS. Recent evidence has implicated cortical reorganization as a mechanism …
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The neuroanatomy of pictorial reasoning in autism
… The work in this thesis combines behavioral, functional MRI, and diffusion tensor imaging methods to examine the neurobiological basis of the discrepancy between linguistic and visuospatial skills in autistic cognition. A pictorial reasoning task, designed to manipulate the degree to which …
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