Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 19 of 19 for “"Functional Brain Networks"”.
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Functional Brain Networks Underlying Anticipation in Motivated Behavior
… and memory, and studies implicate reward-related brain circuitry. However, few studies have investigated the neural underpinnings of anticipation on a brain-wide network scale . In this set of experiments, I take an interdisciplinary cross-species approach, using in-vivo electrophysiology in mice …
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Age-Related Changes in Human Anatomical and Functional Brain Networks
… changes in specific connections. We find that functional connections within and between intrinsic connectivity networks (ICNs) follow distinct lifespan trajectories. We further characterize these changes in terms of each ICN’s “modularity” and find that most ICNs become less modular (i.e. less …
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Resting-State Functional Brain Networks in Bipolar Spectrum Disorder: A Graph Theoretical Investigation
… However, existing neuroimaging research on functional connectivity between frontal and limbic brain regions remains inconclusive, and is unable to adequately characterize global functional network dynamics. Graph theoretical analysis provides a framework for understanding the local and …
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Characterising disease-related and developmental changes in correlation-derived structural and functional brain networks
Human structural and functional brain architecture is increasingly studied by applying the mathematical framework of complex networks to data from magnetic resonance imaging. Connections (edges) in such brain networks are commonly constructed using correlations of features between pairs of brain …
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Topology matters: characteristics of functional brain networks in healthy subjects and patients with Epilepsy, Diabetes, or Amyotrophic Lateral Sclerosis during a resting-state paradigm.
The brain can be seen as a complex structural and functional network. Cognitive functioning strongly depends on the organization of functional brain networks. EEG/MEG resting-‐state functional connectivity and functional brain networks studies attempt to characterize normal brain organization as …
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A Method for Analyzing Community Dynamics in Temporal Networks Applied to Emotional Recollection in fMRI Data
Temporal networks exhibit evolving patterns of connectivity, making the study of community organization a critical component of their analysis. Communities within a network are characterized by entities displaying higher interconnectivity within the community than outside it. In temporal networks, …
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A role for nutrition in healthy brain aging
… understand nutrition’s impact on cognition and brain health across the life span. While accumulating evidence indicates healthy cognitive aging is dependent upon both brain health and nutritional status, the relationship between nutrition, cognition, and brain structure and function remains to …
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The distinct contributions of cardiovascular risk factors to cognitive ageing
… what is good for the heart is also good for the brain. However, it is not clear whether different aspects of cardiovascular health – such as blood pressure or heart rate – affect the brain through shared or independent pathways, partly because they are often condensed into a single composite …
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Effects of methamphetamine on prenatally exposed children in Cape Town: cognition and intrinsic functional brain connectivity
… exposure (PME) on cognition and the developing brain in a sample of affected children in Cape Town, South Africa. Thus, this is a two-part study: the first part examines the effects of PME on neuropsychological outcomes, and the second part examines the effects of PME on intrinsic functional …
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Vascular Risk, Functional Connectivity, and Episodic Memory in Older Adults
<p>Resting-state functional magnetic resonance imaging and functional connectivity (FC) analyses are used to explore functional brain networks underlying a diverse array of abilities. Functional networks are composed of regions throughout the brain whose activity is closely linked to form a …
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Differences in resting state functional networks in HIV infected and uninfected children at age 7 years
… therapy (HAART) in infants provides the brain some protection against HIV damage, few studies have examined the long-term effects of HIV infection and HAART on neurodevelopment, and none have measured their impact on functional brain networks in young children. We use resting state …
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Connectivity biomarkers in neurodegenerative tauopathies
… and how the anatomical and neurochemical networks that underlie clinical features might be altered by disease. I investigate simple clinical biomarkers, showing that a two-minute test of verbal fluency is a potential diagnostic biomarker to distinguish between PD and PSP and that the ACE-R …
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On the origins of glioma: insights from brain network mapping
Glioma tumours are among the most lethal brain disorders, claiming the lives of thousands of people in the United Kingdom each year. Despite the severity and prevalence of the condition, remarkably little is understood about the origins of gliomas, or the mechanisms that guide their spread within …
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Lifestyle factors and neuroimaging metrics as predictors of cognitive performance in healthy aging
… changes in the structure and functioning of the brain that lead to impairments in multiple cognitive functions. The trajectories of age-related effects on the brain and cognition exhibit considerable differences across cognitive domains and across individuals, and investigating approaches and …
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A neuroimaging study to characterise adolescent major depressive disorder, the effects of cognitive behavioural therapy, and potential subtypes based on familial loading
… it is still unclear as to what deviations of brain structure and function actually occur in adolescent MDD. Furthermore, though much of the past literature has claimed that cognitive behavioural therapy (CBT) has a normalising effect on disrupted brain function in adolescent MDD, this has not …
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Evaluating the cognitive benefits associated with an acting intervention: A brain-behavior framework
… Aging affects the configuration of large-scale functional brain networks with a corresponding decline in higher-order cognitive function. These cognitive changes can often compromise the ability to function independently. Previous research has suggested that the aging brain exhibits plasticity, …
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Computational methods for analyzing wide-field calcium neuroimaging data
Submission published under a 24 month embargo labeled 'U of I Access', the embargo will last until 2026-05-01
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Revealing the plastic brain with functional connectivity: effects of exercise on brain plasticity and cognition
… about precisely how exercise effects on the brain benefit human cognition (Cotman and Berchtold, 2002; Kramer and Erickson, 2007). In this thesis I examine effects of physical activity on age-related deficits in brain function and cognition, followed by an examination of potential explanatory …