Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"Functional Biomarker"”.
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Identification of DNA Copy Number-Dependent Transcriptional Deregulation inHepatocellular Carcinoma (HCC)
… RNA-mediated knock-down experiment revealed the functional relevance of IER3 in liver cancer progression. In conclusion, the results of this study suggest that genomic copy number alterations with transcriptional deregulation at 6p21-24 identify an aggressive HCC phenotype and a novel functional …
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Two methods of biomarker discovery: applications in neuropathic pain and pharmacotherapy.
Biomarkers have potential utility in the treatment of pain as diagnostics and for quantification of drug efficacy and safety. A qualified biomarker will capture overlapping disease mechanisms and will be responsive to treatment. The necessity for these strict requirements renders it difficult to …