Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 111 for “"Functional Activity"”.
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Functional Activity and Switching of Novel Cannabinergic Ligands
… This research seeks to better understand the functional mechanism of cannabinoids, in the hopes of ascertaining which molecular attributes confer desirable selectivity and functional activity.</p> <p>Looking first at classical benzchromene core analogues, we have shown that presence of an …
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Submembrane cytoskeleton-regulated assembly and functional activity of gap junctions
Connexine formen gap junctions, die den Transfer von Ionen, Metaboliten und second messengers zwischen sich berührenden Zellen vermitteln. An vielen Funktionen der Connexine, z.B. zellulärer Transport, Plaquebildung und -stabilität sowie Kanalleitfähigkeit sind Proteine beteiligt, die an die …
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Design, Implementation and Analysis of Functional Activity and Connectivity in Patterned Neural Networks
… with investigating the issues related to the functional connectivity of biological neuronal networks. In particular, low density neuronal cultures grown on predefined patterns are found to provide suitable test beds for such studies. Likewise, microelectrode array technology serves as a …
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EFFECTS OF SOCIAL DOMINANCE ON THE MORPHOLOGICAL AND FUNCTIONAL ACTIVITY OF THE DIENCEPHALIC POSTERIOR TUBERCULAR DOPAMINERGIC NUCLEUS IN ZEBRAFISH (DANIO RERIO)
… social dominance affects the structural and functional organization of the diencephalic Posterior Tubercular Dopaminergic Nucleus (PTN) in zebrafish (Danio rerio). The PTN integrates visual and olfactory information, which are relayed to the spinal cord to modulate swimming and startle escape …
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The effect of the functional stimulation of the abdominal muscles on functional activity in patients with stroke: a feasiblity [sic] study
… rehabilitation of patients with stroke. Functional Electrical Stimulation (FES) of the abdominal muscles is an intervention which may result in increasing the activation of these muscles and improving proximal stability and function. However the effects of FES, although proved useful in …
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Occupational Therapists: A Study of Managing Multiple Identities
… from the data were: Therapist as catalyst of functional activity, Therapist as envoy of profession, Therapist as navigator of bureaucracy, and Therapist as member of interdisciplinary team. Therapist as catalyst of functional activity proves to be the preferred identity of occupational …
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Occupational Therapists: A Study of Managing Multiple Identities
… from the data were: Therapist as catalyst of functional activity, Therapist as envoy of profession, Therapist as navigator of bureaucracy, and Therapist as member of interdisciplinary team. Therapist as catalyst of functional activity proves to be the preferred identity of occupational …
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A multimodal investigation in eye movements
While functional magnetic resonance imaging (fMRI) has identified which regions of interest (ROIs) are functionally active during a vergence movement (inward or outward eye rotation), task-modulated coactivation between ROIs is less understood. This study tests the following hypotheses: (1) …
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Subacute immunotoxic effects of the environmental contaminants 7,12-dimethylbenzanthracene (DMBA), hexachlorocyclohexane (lindane), and 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on spleen and pronephros cellularity and morphology and functional activity of macrophages contained in these hematopoietic organs in the cichlid fish tilapia (<i>Oreochromis niloticus</i>)
… the spleen and pronephros were assessed, as were activity of phagocytic celis contained in these hematopoietic organs. <p>Using chemical doses which produced no clinical toxicity, tilapia exposed to each chemical agent displayed a significant reduction in total cell number of both spleen and …
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Quantification of neural substrates of vergence system via fMRI
… of the eyes. Neuroimaging methods such as functional magnetic resonance imaging (fMRI) measure neural activity changes activity in the brain while subjects perform experimental tasks. A rich body of primate investigations on vergence is already established in the neurophysiology literature; …
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UNDERSTANDING THE RELATIONSHIP BETWEEN ONCOLYTIC AD5 DELETED E1b55KDA LYTIC INFECTION AND P53 IN MAMMALIAN CELLS
… the relationship between p53 status, levels and functional activity, and oncolytic Ad5dlE1b55kDa replication efficiency. Firstly, five transient p53 expression vectors that contain different regulatory elements were engineered and then evaluated in H1299, HEK293 and HeLa cell lines. Data …
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Identification of the factors impacting immunosorbent performance
… antibody columns. This is in part due to the low functional activity of immobilized antibodies and the high cost of pathogen free antibody. The objective of this research was to detail the impact of orientation, multipoint attachment and high local density upon the functional activity of …
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The Role of Aerobic Glycolysis in the Resting Human Brain
… oxidative phosphorylation. Elevation in neuronal activity increases aerobic glycolysis due to the disproportionate increase in blood flow and glucose utilization greater than oxygen consumption. Since aerobic glycolysis produces significantly less energy than complete oxidation of glucose, its …
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Migrena sergančių moterų ląstelinės hemostazės ir periferinių kraujagyslių kitimai /
… of cellular hemostasis, as well as changes in functionality and stiffness of endothelium of peripheral blood vessels of various diameter during period between the attacks. 60 healthy women, as well as 30 with MA and 30 with M0 participated in the research. Higher systolic and diastolic blood …
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In Vitro studies of factors which may influence ligand binding, function, immunogenicity and genetic regulation of the Beta-2 adrenergic receptor in asthma
… influence the expression, ligand binding and functional activity of the beta-2 adrenergic receptor. These studies were prompted by previous reports that the postulated beta-2 adrenergic receptor abnormality in allergic asthma could be induced, induced by autoantibodies. I established and …
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Function follows form : how connectivity patterns govern neural responses
… processing that underlies the patterns of functional activity in the brain. By combining diffusion-weighted imaging or DWI, with fMRI, we are able to non-invasively measure connectivity and neural responses in the same individuals and directly relate these two measures to one another. In …
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Effect of Photoperiod on Developmental Morphology and Enolase Isoenzyme Immunohistochemistry in Rat and Djungarian Hamster Superficial Pineal Glands
<p>The best understood functional activity of the pineal gland is its diurnal production of melatonin in response to environmental lighting cues. Several enzymes of the melatonin pathway respond to daily photoperiod changes, for example hydroxyindole-O-methyltransferase (HIOMT) and serotonin …
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Modulation of the activity of a key metabolic regulator Small Heterodimer Partner by post-translational modifications
… a putative ligand binding domain. SHP forms non-functional heterodimers with DNA binding transcriptional factors and, thereby, functions as a transcriptional corepressor in diverse biological processes, including cellular metabolism, cell proliferation, apoptosis, and sexual maturation. Of these …
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Retroviral-Medicated Transfer of Suppressor tRNA Genes Into Human Cells
… acid, and allow translation of a full-length, functional protein. Human opal arginine suppressor tRNA genes that encode the structural portion of the tRNA and about 15 bases from the 3' flanking sequence were synthetically constructed using oligonucleotides. Retroviral vectors were selected for …
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On the interdependence of pancreatic size, and tissue composition and cellularity, and growth : characterization of a caerulein-generated model of enhanced pancreatic growth in the adult male rat
… indeces of cellular size, and of differentiated functional capacity, in relation to an index of cell proliferation within the pancreatic acinar parenchyma. We have characterized pancreatic wet weight, two major cellular biochemical constituents with respect to their glandular levels and in vivo …
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