Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 31 for “"Functional Activation"”.
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Characterisation of T cell specificity, functional, activation and memory profiles associated with QuantiFERON TB Gold conversion and reversion
… of changes in M.tbspecific CD4 T cell functional, memory and activation profiles associated with QFT conversion (acquisition of M.tb infection) and reversion (potential M.tb clearance). Our first aim was to characterise the homing, cytotoxic and functional capacity of M.tbspecific …
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Functional activation of the p53 tumor suppressor in non-tumorigenic variants of the HeLa cervical carcinoma cell line
Thesis (Sc. D.)--Massachusetts Institute of Technology, Division of Toxicology, 1996.
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Functional Activation Patterns in Pediatric-Onset Multiple Selerosis: Does Physical Activity Play a Role in the Maintenance of Working Memory
… memory task, while participants underwent functional neuroimaging. Participants also completed a neuropsychological battery and structural imaging in a 3T scanner. Findings suggest that inefficient processing and/or compensatory recruitment occurs in cognitively-preserved POMS patients for …
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Neural Alterations Influencing Skilled Reading In Adhd: A Task-Based Fmri Study
… nor the association are well understood from a functional neuroimaging perspective. The goal was to assess to what extent ADHD/+RD differ from ADHD without RD (ADHD/-RD) and typically developing controls (TDC) in functional activation of attention- and reading-related areas during various tasks. …
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Frequency-Domain Near-Infrared Spectroscopy in the Human Brain
… these quantities change over time during rest, functional activation, pathology, and disease. My dissertation describes the development, signal analysis, validity, and clinical feasibility of FD-NIRS and how useful the information may be for general health knowledge and preventive medicine.
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Investigating the Functional and Structural Neural Correlates Associated With Dance Expertise
We investigated the structural and functional plasticity associated with dance expertise in a cross-sectional pilot study, comparing ballet dancers to controls. Using fMRI, the whole-brain functional activation maps of dancers and controls engaged in motor imagery of dance movements were compared. …
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Obtaining optimal data length for FMRI images
… in state of the art research within the field of functional Magnetic Resonance Imaging (fMRI). FMRI enables research to be conducted on brain mapping in healthy individuals, as well as in patient populations. The need for accurate functional images is required. The primary objective was the …
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Functional MRI Activation of Inhibitory Control in Adolescents and Young Adults with Multiple Sclerosis
… functions. This study examined the concept of functional reorganization concerning inhibitory control using a simple Go/No-go (GNG) functional MRI paradigm in pediatric-onset MS. The control group demonstrated greater functional activation as compared with the patient group in several regions: …
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Spatial alignment of functional regions in fMRI
… step for discovering a common structure in brain activation regions from multi-subject fMRI data is the ability to find spatial correspondences across subjects. This has proven to be a challenging problem due to the lack of a ground truth and variability in anatomical brain structure, functional …
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Exploring the functional organization of cerebral cortex using data from the Human Connectome Project
… detailed topography of structural features and functional activation maps in cerebral cortex. In my thesis, I will describe three studies that were conducted using the HCP database. In the first study, I tested genetic influences on the organization of category-selective areas of visual cortex. …
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Techniques for Approximating Optimal Linear Estimators of Multidimensional Data
… improves the ability to detect low CNR functional activation in small regions of activation without a compromise to the false detection rate. Finally, the concepts developed for the multidimensional estimation framework are used to illustrate how regularized reconstruction of noisy …
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Statistical methods for fMRI data analysis
Since the early 1990s, functional magnetic resonance imaging (fMRI) has dominated the brain mapping field and it has been proved a powerful tool for mapping human brain functions. The fMRI is a high spatial-temporal resolution medical-imaging modality, which means the data structure is complicated …
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Magnetic resonance imaging of the cerebral metabolic rate of oxygen (CMRO₂)
… and will change in settings of disease and functional activation. Accurate CMRO₂ measurement will enable detailed investigation of neuropathology and facilitate our understanding of the brain's underlying functional architecture. Despite the importance of CMRO₂ in both clinical and basic …
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Investigating immune surveillance, tolerance, and therapy in cancer
… a higher level of costimulation to achieve functional activation.
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Cognitive neuroscience of training and transfer in working memory and visual attention
… performance was accompanied by decreases of functional activation within anatomically circumscribed regions of frontal and parietal cortex as well as more wide-spread increases in frontoparietal functional connectivity (Experiment 2). Visual attention training using adaptively adjusted speeds …
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Foxo Transcription Factors Control Spermatogonial Stem Cell Self-Renewal and the Initiation of Spermatogenesis
… from Foxo3 and Foxo4. Conditional inactivation of PI3K/Akt pathway components in the male germ line confirmed that PI3K signaling regulates Foxo1 stability and subcellular localization, revealing that the Foxos are crucial effectors of PI3K/Akt signaling in SSCs. The nuclear …
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Investigating Cerebral Function in Neonates Using Diffuse Optical Tomography
… early stages of vocal specialisation. In this functional activation study, the cerebral haemodynamic changes observed in response to vocal and non-vocal stimuli are presented in Chapter 6. In recent years, the study of spontaneous cerebral activity that gives rise to resting state networks …
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Magnetic particle imaging for intraoperative breast cancer margin assessment and functional brain imaging
… during breast-conserving surgery (BCS), and functional neuroimaging. For margin assessment in BCS, a hand-held Magnetic Particle detector and a small-bore MPI imager are assessed for intraoperative use along with an injected SPIO agent. The goal is to detect positive margins during surgery …
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The Neural Correlates of Allocentric Spatial Memory in Schizotypy
… using the Schizotypal Personality Questionnaire. Functional and structural MRI was used to investigate the neural correlates of allocentric spatial memory in schizotypal personality. Allocentric spatial memory is reported to be impaired in schizophrenia and this is thought to be related to …
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