Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 6 of 6 for “"Function of gene"”.
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Loss of function of Gene X protects against α-dicarbonyl stress through the skn-1 pathway in C. elegans
… in prevalence worldwide. One potential cause of these diseases is the accumulation of advanced glycation end products (AGEs), which are macromolecules that cause irreversible damages. AGEs are a diverse group of highly oxidative byproducts produced from α-dicarbonyl compounds (α-dcs), which …
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Magnetic targeted drug delivery system in gene therapy
… system is a method to transport the drug of the required amount accurately to the targeted diseased part. Recently, the concept of Magnetic Targeted Drug Delivery System (MTDDS), based upon magnetic particles under the action of an external magnetic field, exhibits considerable potential …
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Identifying and Characterizing Transition Cells in Developmental Processes from scRNA-Seq Data
<p>During the development of multicellular organisms, individual cells make distinct decisions about their cell types and states. Understanding the molecular mechanisms underlying cellular state transitions at different developmental stages provides deep insights into physiology, morphology and the …
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Characterizing cell-cycle as a global regulator of stochastic transcription and noisy gene expression in S. cerevisiae
Even in the same environment, genetically identical cells can exhibit remarkable variability, or noise, in gene expression. This expression noise impacts the function of gene regulatory networks, depending on its origins. Hence, a prerequisite for understanding or designing gene regulatory networks …
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Funtional Analysis of the Murine Genes, MOCS1 and Sox15
In dieser Arbeit wurden die Funktionen der Mausgene, MOCS1 und Sox15, untersucht. Molybdän Cofaktor-Defizienz ist eine seltene und schwere autosomal-rezessive Krankheit beim Menschen, für die keine Therapie bekannt ist. Das Fehlen von aktiver Sulfitoxidase, die ein Molybdän Cofaktor-abhängiges …
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Nonstationary metabolic flux analysis (NMFA) for the elucidation of cellular physiology
Many current and future applications of biological engineering hinge on our ability to measure, understand, and manipulate metabolism. Many diseases for which we seek cures are metabolic in nature. Small-molecule biomanufacturing almost always involves metabolic engineering. Biofuels, a current …