Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 9 of 9 for “"Fructose-1,6-bisphosphate"”.
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Purification and Characterization of glpX-Encoded Fructose 1,6-Bisphosphatase, a New Enzyme of the Glycerol 3-Phosphate Regulon of Escherichia coli
… In the present work, we show that glpX encodes a fructose 1,6-bisphosphatase (FBPase), which catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate and phosphate. The purified FBPase was dimeric, dependent on Mn2+ for activity and exhibited an apparent Km of 35 μM for …
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Gluconeogenic FBP1 plays a key metabolic role in activated T cells
Fructose bisphosphatase-1 (FBP1) is a rate limiting enzyme in gluconeogenesis that converts fructose-1,6-bisphosphate (F1,6BP) to fructose-6-phosphate (F6P). It is active in liver, kidney and skeletal muscle cells. This study suggests that FBP1 plays a novel non-gluconeogenic role in T cells. …
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The Effects of 3-Phosphoglycerate and Other Metabolites on the Activation of AMP-Activated Protein Kinase by LKB1/STRAD/MO25
… metabolites including glucose-6-phosphate (G6P), fructose-6-phosphate (F6P), fructose 1,6-bisphosphate (F1,6-P2), 3-phosphoglycerate (3PG), glucose-1-phosphate (G1P), glucose-1,6-bisphosphate (G1,6-P2), adenosine diphosphate (ADP), carnitine (Carn), acetyl-carnitine (Acarn), inosine monophosphate …
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Quinolines: Novel Synthesis and Derivatives of Heterocyclic Bioactive Agents
… tuberculosis's</em> class II fructose-1,6-bisphosphate aldolase presents an interesting target in the design of new therapies against this disease. Previous attempts to construct an inhibitor to this enzyme fell short due to poor selectivity or poor cellular uptake. However a …
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A Study of the Effects of Polyethylene Glycol on Interactions Between Glycolytic Enzymes and F-Actin, and Among Glycolytic Enzymes
… hydro-lyase (enolase, EC 4.2.1.11), D-fructose-1,6-bisphosphate D-glyceraldehyde-3-phosphate lyase (aldolase, 4.1.2.13), D-glyceraldehyde-3-phosphate:NAD$\sp{+}$ oxidoreductase (GAPDH, EC 5.3.1.1), D-glucose-6-phosphate ketol-isomerase (GPI, EC 5.3.1.9), (S)-lactate:NAD+ oxidoreductase …
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Enhanced methylglyoxal formation in cystathionine γ-lyase knockout mice
… renal MG levels, we found that the activity of fructose-1,6-bisphosphatase (FBPase), the rate-limiting enzyme in gluconeogenesis, was significantly down-regulated, along with lower levels of its product (fructose-6-phosphate) and higher levels of its substrate (fructose-1,6-bisphosphate) in the …
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Assessing the effects of genetic modifications on photosynthetic capacity in Nicotiana tabacum (tobacco) and Glycine max (soybean)
… in the binding specificity of ribulose-1,5-bisphosphate carboxylase/oxygenase for carbon dioxide, one encodes a gene for expression of a bicarbonate transporter, and one overexpresses the native rubisco by 15%. Plants were phenotyped in an agricultural field trial and then in two controlled …
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Identification of Novel Allosteric Regulators of Human Erythrocyte Pyruvate Kinase
… molecules that bind to the allosteric activator fructose 1,6-bisphosphate (FBP) binding site of R-PK to identify compounds that could interact with the protein. The software UNITY, as present in the molecular modeling software Sybyl was used to perform 3D searches against the National Cancer …
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Utilização da frutose-1, 6-Bisfosfato como um protetor celular na preservação de fígados para transplante
A solução de preservação da Universidade de Wisconsin (UW) é considerada a solução padrão para preservação de fígados, rins e pâncreas. A frutose-1,6-bisfosfato (FBP) é uma substância que apresenta efeito protetor do fígado contra injúrias provocadas por agentes químicos e ocorridas durante o …