Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"Frizzled (Fzd)"”.
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Eukaryotic protein mimicry as an infection strategy for Ehrlichia chaffeensis
… through direct interaction with the Wnt pathway Frizzled (Fzd) family of receptors. In this study, we used immunofluorescence microscopy to demonstrate very strong colocalization between E. ch. and Fzd2, 4, 5, 7, and 9, as well as coreceptor LRP5 1-3 h post infection. Direct binding between …
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Novel Insights into the Role of the Smoothened Cysteine Rich Domain in Hedgehog Signalling
… CRD of the Smo receptor is homologous to the Frizzled (FzD) CRD. The FzD CRD interacts with the physiological ligand of the FzD receptor: Wnt, but the function of the Smo CRD is not clearly elucidated.</p> <p>In the present dissertation we determined the first structure of the Drosophila Smo …
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Wnt Signaling in Growth Cone Mediated Neurite Outgrowth from Spiral Ganglion Neurons in the Adult Mouse
… roles of Wnt proteins signaling through their Frizzled receptors in neuro-regeneration in the adult inner ear despite their involvement in axon guidance, dendrite morphogenesis, and synapse formation throughout the developing nervous system. In Chapter II, I show the differential expression of …