Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 8 of 8 for “"Friend virus"”.
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The Isolation of Friend Virus Protein by Zonal Centrifugation
The problem. Isolation of Friend virus protein in an increased yield for immunological purposes by zonal centrifugation was the purpose of this experiment. Procedure. Sucrose gradient zonal centrifugation was used to isolate Friend virus polysomes. The concentration of the polysomes and the removal …
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The Effect of Leucogenenol on Classical Chemotherapy and Immunotherapy of Friend Virus Disease
… in combination with Methotrexate chemotherapy on Friend Virus Disease. Procedure. FV infected mice were treated with various combinations of the chemo-and immunotherapeutic agents being investigated. Three parameters of the disease, survival time, ratios of spleen and liver weight to total body …
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Mechanisms of Erythroid Proliferation and Differentiation: Analysis of the Role of Erythropoietin Receptor in the Friend Virus Model
… for erythroid survival. In this study, we used Friend disease as a model system to understand the role of EPOR signaling in both Friend disease and normal erythropoiesis. Here we showed that EPOR signaling is not essential for Friend virus-mediated erythroblastosis. However, both EPOR and signal …
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The Effect Of Leucogenenol and Chemotherapy on B and T Lymphocyte Populations in Mice Infected With Friend Virus Leukemia
… T lymphocyte populations of mice infected with Friend virus leukemia. Procedure. Isolated lymphocyte populations were quantitated using a cytotoxic assay for T lymphs and a direct immunofluorescent technique for B lymphs. Spleen and liver weight to total body weight ratios, survival times, …
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Role and specificity of regulatory T cells during retroviral infection
… infection of the hematopoietic system, both virus-mediated and immune-mediated effects may cause bone marrow dysfunction leading to cytopenias. To study the pathological consequences of the T helper response to unresolving chronic infection, a system was developed using infection of …
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Untersuchungen zur Rolle von zytotoxischen Molekülen bei der Immunabwehr gegen Retroviren
… Die Infektion von Mäusen mit dem retroviralen Friend Virus Komplex (FV) wurde daher als Modell verwendet, um die antiviralen Mechanismen gegen Retroviren aufzuklären. Als erstens wurde die Beteiligung von CD8+ T-Zellen bei der Kontrolle der FV Infektion in Depletion-Experimenten gezeigt. In …
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Die Rolle von bakteriellen DNA-Sequenzen (CpG) bei der Immuntherapie von retroviralen Infektionen
… DNA mit CpG-Motiv (CpG-ODN) bei einer akuten Virusinfektion beschrieben. Als experimentelles Modell wurde das Friend Virus (FV), ein muriner Retroviruskomplex, verwendet. Das FV kann in Mäusen eine tödlich verlaufende Erythroleukämie induzieren. Durch die Immuntherapie mit CpG-ODN in der …