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Showing 1 to 20 of 34 for “"Francisella"”.
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Site-Directed Mutagenesis in Francisella Tularensis by Allelic
Francisella tularensis is a Gram-negative, facultative intracellular coccobacillus and the etiologic agent of tularemia for a wide variety of vertebrate and invertebrate animal species. Several species and subspecies of Francisella are currently recognized. However, the majority of infections are …
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The Potential Role for CapB in Pathogenesis of Francisella tularensis
Francisella tularensis was a facultative intracellular pathogen and a gram-negative coccobacillus which has been categorized by the CDC as a potential class A select agent due to its highly infectious properties and high mortality rates. Francisella tularensis was also responsible for the zoonotic …
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Interactions of Francisella Tularensis With Components of the Host Fibrinolytic System
<p><em>Francisella tularensis</em> (FT) is a Gram-negative coccobacillus and causative agent of a life-threatening disease commonly referred to as tularemia. Due to the highly infectious nature of the organism, its previous development as a biowarfare agent and its potential use in acts of …
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Identification and Characterization of the Hfq protein and small RNAs in Francisella novicida
<italic>Francisella tularensis</italic> is the causative agent of the disease tularemia and a potential bioterrorism agent. Few regulators have been identified in this organism and little is known about its genetic regulatory networks. In this dissertation project, culture-based and molecular …
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Identification and characterization of a novel capsule-like complex surface antigen of Francisella tularensis
Francisella tularensis is a highly virulent zoonotic pathogen that is the causative agent of tularemia in humans. Two subspecies of F. tularensis are the most virulent in humans: tularensis (type A) and holarctica (type B), with less than 10 organisms via aerosol of a type A strain having the …
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Identification and characterization of the acid phosphatase from Francisella tularensis and its potential role in pathogenesis
Successful intracellular pathogens resist or prevent the formation of antimicrobial substances produced by professional phagocytes including, toxic oxygen intermediates of the respiratory burst. Purified acid phosphatases (ACP) from Leishmania donovani and Legionella micdadei have been shown to …
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Surface Polysaccharides of Francisella tularensis: Further Characterization, Role in Virulence, and Application to Novel Vaccine Strategies
Francisella tularensis is a Gram-negative, zoonotic bacterium that causes tularemia in animals and humans. The two subspecies tularensis (Type A) and holarctica (Type B) are considered Tier I Select Agents due to the bioweapon potential of these subspecies. Type A strains, considered the more …
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Mechanisms Involved in Enhanced Protection Against Gram Negative Bacterium Francisella tularensis Utilizing an FcR Targeted Vaccine Platform
<p>Francisella tularensis is a gram-negative intracellular bacterium and the etiologic factor of a potentially fatal disease tularemia. Due to its high infectivity the Centers for Disease Control and Prevention has designated F. tularensis as a Category A biological agent. Nevertheless, the …
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Infection Rates of Amblyomma Americanum and Dermacentor Variablis by Francisella Tularensis and Borrelia Lonestari in Southwest Missouri
<p>Francisella tularensis and Borrelia lonestari are the bacteria that cause tularemia and erythema migrans-like rash, respectively. F. tularensis is capable of being transmitted to humans through the bite of an infected Amblyomma americanum tick or Dermacentor variabilis tick, while the primary …
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Characterization of the Bacterial Microbiome of Exotic Tick Species Collected from Migratory Birds
… bacteriome was predominantly dominated by <em>Francisella, </em>with a varying abundance of <em>Rickettsia, Candidatus Midichloria mitochondrii </em>and<em> Cutibacterium </em>(actinobacteria). Co-occurrence of <em>Coxiella </em>and <em>Francisella </em>were observed in three species: …
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Zoonosis bacterianas transmitidas por animales de compañía diagnosticadas en el Hospital Universitario Central de Asturias y papel de los perros como reservorio de genes de resistencia a los antimicrobianos
… canimosus, Pasteurella multocida, Afipia felis y Francisella tularensis, todas ellas asociadas a la convivencia con estos animales. Asimismo, se analizó el rol de los perros sanos como posibles portadores de enterobacterias resistentes a los antimicrobianos.
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Genomic Instability and Gene Dosage Obscures Clues to Virulence Mechanisms of F. tularensis species
The pathogen Francisella tularensis subsp. tularensis has been classified as a Center for Disease Control (CDC) select agent. However, little is still known of what makes the bacteria cause dis-ease, especially the highly virulent type A1 strains. The work in this dissertation focused on type A1 …
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Prevalence and environmental risk factors for ten zoonoses in two cree communities of James Bay (Canada
… are: Leptospira sp. (23%), Coxiella burnetii, Francisella tularensis (17%, titer > 1/20), Toxoplasma gondii (5%), the Sin Nombre virus (0%), two of the virus of the California serogroup (10%) (Snowshoe hare and Jamestown Canyon viruses) and of than less 5% for Echinococcus granulosus, Toxocara …
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Fabrication of intensity-based Long-Period-Gratings fiber sensor with CO2 Laser
… Staphylococcus aureus (MRSA), Francisella tularensis, and so on. We have previously demonstrated that a UV-induced long-period-grating (LPG) based fiber sensor is extremely sensitive to small variation of refractive index (RI) and thickness of the surrounding medium. In this …
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Comparative Genomics of Selected Species of Gram-Negative Bacteria
… to facilitate the finishing of the genome of \(Francisella\) \(tularensis\) strain FSC198, using sequence information from strain Schu S4. The completed genome sequence of FSC198 showed it to be almost identical to that of Schu S4. The two genomes differ at only 11 loci, eight SNPs (single …
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Some diseases and parasites affecting cottontail rabbits in Virginia
… avian species, and tested for antibodies against Francisella tularensis. Evidence of infection was found in 5 raccoons, 3 opossums, 1 striped skunk, 1 Norway rat, 1 chipmunk, 1 white-tailed deer, and 1 bobwhite quail. This indicated that tularemia was present at Fort Pickett in a number of species …
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