Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 12 of 12 for “"Fragility fracture"”.
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The clinical characteristics, complications and treatment outcomes of patients with osteoporosis at Groote Schuur Hospital
… as the population ages. An osteoporotic fracture is associated with a high rate of morbidity and mortality. Data on the prevalence, risk factors and outcome of osteoporotic fractures in South Africa remains sparse. Method: A retrospective audit was undertaken in all patients attending the …
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MUSCULOSKELETAL STRENGTH, FALL AND FRACTURE RISK IN EARLY POSTMENOPAUSAL WOMEN
… over the first year following a distal radius fracture (DRF), and evaluate differences in fall and fracture risk factors in women over the age of 50 years with a DRF compared to their non-fractured peers. Methods: Two cohorts of participants volunteered in two sub-studies of the thesis. The …
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The management of fragility fractures of the hip: a quality assessment project
Introduction: Fragility fractures of the hip (FFH) constitute the most serious complication of osteoporosis carrying a mortality rate of up to 20 – 30% in the first year after injury and are associated with post injury decay in patient's level of activity in more than 50% of the cases. It is also a …
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Bone turnover markers and prediction of bone loss in elderly women
Around 70,000 osteoporosis-related fractures occur in Sweden annually and approximately half of the women in western world will sustain a fragility fracture after the age of 50 years. Fracture preventive efforts require the identification of individuals who are at high risk. Biochemical markers of …
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Role of the RUNX2 rs59983488 variant in bone mass determination and fracture risk in Malta
… bone microarchitecture, leading to an increased fragility fracture risk. The Runt-related Transcription Factor 2 (RUNX2) protein encoded by the RUNX2 gene is involved in the maturation and differentiation of osteoblasts and chondrocytes that are, crucial for endochondral bone formation. The RUNX2 …
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Extrapancreatic actions of incretin-based therapies on bone in diabetes mellitus
… mechanical strength, leading to increased bone fragility. The incretin hormones, with a classical effect to increase insulin secretion following food ingestion, are now postulated to have important direct effects on bone. As such, glucose-dependent insulinotropic polypeptide (GIP) has dual …
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Peak Bone Mass, Lifestyle Factors and Birth Weight: A study of 25-year old women
… give symptoms until the ultimate outcome, the fragility fracture occurs. Regulation of bone mass is controlled by genetic, environmental and nutritional influences. Peak bone mass, defined as the maximum bone mass accrued, is usually reached by the third decade of life and is an important …
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Exercise in Youth and Long-Term Effects on Bone and Joints
… population, the number of osteoporosis-related fractures and osteoarthritis (OA)-related hip and knee arthroplasty procedures is increasing. The individual suffering and the burden on society for these conditions is immense. Genetic contribution for the variance in bone mineral density (BMD) is …
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Bone health in Gambian women: impact and implications of rural-to-urban migration and the nutrition transition
… been linked with the recent rise in osteoporotic fragility fracture incidence in many countries. Predictions indicate that hip fracture incidence will increase 6-fold in Africa and Asia by 2050, partially attributed to demographic transition and population ageing. Differences in areal bone mineral …
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Risk factors for bone fragility and fracture in postmenopausal women
… thesis was to evaluate risk factors for bone fragility and fractures in postmenopausal women in a long-term perspective. The study period spanned from the age of 48 to age 82 and is thus unique in its length. The studied sample was homogeneous and consisted of 390 north European women from a …
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Physical activity and its effect on bone in the short- and long- term perspective.
… worldwide where Sweden has one of the highest fragility fracture incidences in the world. The growing years are thought to be an opportune time to build strong bones and the enhancement of peak bone mass (PBM) has been suggested as a prevention strategy for osteoporosis. Most exercise …
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Silent slips trips and broken hips: the recovery experiences of young adults following an isolated fracture of the proximal femur
Isolated hip fracture following a minor fall is a serious injury, normally requiring urgent surgical treatment and a complex recovery journey. Although commonly associated with the elderly, incidence and impact in adults under 60 years of age may be underestimated. The extensive literature almost …