Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"Fragile site FRA3B"”.
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The Origin of Genome Instability in Cancer: Role of the Fragile Site Gene Product FHIT
… genomic alterations are first seen at chromosome fragile sites. These fragile sites are exquisitely sensitive to agents that stress DNA replication forks, and thus, it is thought that replicative stress is a major source of genome instability in cancer. A frequent and very early genetic alteration …
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Mechanisms and consequences of DNA damage, response and apoptosis in spermatozoa.
… comparing the DSB frequencies at the two most fragile genomic loci (fragile sites FRA3B, FRA16D) in human and murine spermatozoa with lymphocytes, significantly increased DSB levels were detected in spermatozoa in both species. This corroborates that spermatozoa are more prone to DSBs than …
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Mechanisms and consequences of DNA damage, response and apoptosis in spermatozoa.
… comparing the DSB frequencies at the two most fragile genomic loci (fragile sites FRA3B, FRA16D) in human and murine spermatozoa with lymphocytes, significantly increased DSB levels were detected in spermatozoa in both species. This corroborates that spermatozoa are more prone to DSBs than …