Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 28 for “"Fourier-transform Ion Cyclotron Resonance."”.
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Characterization of Cucurbituril Complex Ions in the Gas Phase Using Electrospray Ionization Fourier Transform Ion Cyclotron Resonance Mass Spectrometry
<p>Host-guest interactions have been well studied in the new century to obtain fundamental insights into supramolecular chemistry. Most of the pioneering works have been done using techniques such as NMR, X-ray crystallography, IR spectroscopy and so on. However, none of these techniques is …
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Profiling the metabolome using Fourier transform ion cyclotron resonance mass spectrometry, optimised signal processing, noise filtering and constraints methods
… profiling, a process involving the identification of metabolites present in biological samples, by applying Fourier transform ion cyclotron resonance mass spectrometry (FT-ICR MS). Three novel methods were developed to improve the quality of mass spectra and their interpretation. The first, …
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Design of the First Analytical Platform for Automated Top Down Proteomics With quadrupole/Fourier Transform Ion Cyclotron Resonance Mass Spectrometry
… FT mass spectrometer. It outlines a two dimensional separations platform that utilizes a 96 well plate nanospray robot to facilitate automated analysis on the mass spectrometer. This thesis also highlights instrument advancements required to improve throughput for observation of protein intact …
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Reactivity Studies of Tridhydropyridine Radical Cautions by using Fourier-Transform Ion Cyclotron Resonance Mass Spectrometry and Advancement of Mass Spectrometric Analysis of Asphaltenes and Degradation Products
… play an important role in a variety of applications in the fields of organic synthesis, organic magnets, and biological activity of organic compounds. Several studies have been published on σ- type carbon-centered mono- and biradicals. Reactive intermediates with three formally unpaired …
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A metabolomic investigation of key cellular processes relating to cancer development and progression.
… metabolites in biological samples. Fourier transform ion cyclotron resonance mass spectrometry (FTICR-MS) combines excellent mass accuracy (ppm
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Organic Sulfur-Bearing Species as Subsurface Carbon Storage Vectors
… suitable form for permanent subsurface sequestration. Natural sulfurization processes in sedimentary organic matter are investigated as mechanisms to generate biologically refractory water-soluble organic molecules. Such molecular vectors could be sequestered in shallow, saline, contaminated …
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Novel approaches to toxicity testing in Daphnia magna
… risk assessment strategies have several limitations, such as linking subcellular changes to higher-level biological effects, and an improved knowledge-based approach is needed. Ecotoxicogenomic techniques have been proposed as having the potential to overcome the current limitations, providing …
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Noncovalent Interactions Between Alkali Metal Cation And Aza/thia-Crown Macrocycles: Mass Spectrometric Techniques And Theoretical Studies
… experimental and theoretical description of cation-aza-crown and thia-crown ether interactions with alkali metal cations. Infrared multiple photon dissociation (IRMPD) action spectroscopy and energy-resolved collision-induced dissociation (CID) techniques were used in conjunction with …
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CHARACTERIZATION OF SEPTIC SYSTEM WASTEWATER AND MUNICIPAL SOLID WASTE LANDFILL LEACHATE
The growing United States population means increasing waste production and a corresponding increase in the use and release of contaminants of emerging concern (CECs). The increasing volume and changing composition of waste poses new challenges for waste management and the protection of ecosystem, …
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The factors and protocols that influence, accuracy, precision and uncertainty of accurate mass measurements by FT-ICR ms to validate the assignment of elemental composition
… is becoming more demanding with the expansion of the number of compounds in need of correct identification and with the limits of elemental analysis; a fast, robust analytical solution is sought. Fourier transform ion cyclotron resonance mass spectrometry (FT-ICR MS) is a very powerful tool …
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Dissociation, relaxation, and oxidation of highly vibrationally excited gas phase metal carbonyl and cluster anions.
Fourier transform ion cyclotron resonance mass spectrometry (FT-ICR) was used to study processes occurring in highly vibrationally excited metal-containing anions. The low-pressure environment of the FT-ICR trapping cell is optimal for the intentional study of nonthermal species. Vibrationally …
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Comprehensive study of a heavy fuel oil spill : modeling and analytical approaches to understanding environmental weathering
… use of heavy fuel oils for power generation is rising. Unlike other refined products and crude oils, a large portion of these heavy oils is undetectable using the traditional gas chromatography-based techniques on which oil spill science has been based. In the current study, samples …
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Investigations of biological interactions by hydrogen deuterium exchange Fourier transform ion cyclotron mass spectrometry: novel methods, automated analysis and data reduction
… is used to investigate biological interactions by Fourier transform ion cyclotron resonance mass spectrometry (FTICR MS). For the first time, a series of oligonucleotides of varying length are interrogated by negative mode gas phase H/D exchange. Data presented describes the reactivity of …
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Comprehensive study of a heavy fuel oil spill : modeling and analytical approaches to understanding environmental weathering
… use of heavy fuel oils for power generation is rising. Unlike other refined products and crude oils, a large portion of these heavy oils is undetectable using the traditional gas chromatography-based techniques on which oil spill science has been based. In the current study, samples …
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Improved mass spectrometry characterization of organic compounds using analyte preconcentration and radio-frequency ionization.
… environmental, and forensic sciences. Detection and identification of volatile organic compounds (VOCs) in real world samples, which are often present at low concentrations and within complex mixtures, require the use of efficient sampling techniques and versatile ionization sources. …
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Altering Nitric Oxide Bioavailability and Lipid Profiles in Endothelial Cells By Polycyclic Aromatic Hydrocarbons in Particulate Matter
… studies have demonstrated a significant association between exposure to particulate matter (PM) and atherosclerosis. Polycyclic aromatic hydrocarbons (PAHs) present in particulate matter, are well known to induce oxidative stress and lipid peroxidation via generation of reactive oxygen species …
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Multidimensional liquid chromatographic separations for proteomics
… orthogonal (mutually independent), multidimensional separation methods must be employed to provide sufficient resolution to characterize the appropriate number of different species. The most common of these methods are two dimensional gel electrophoresis (2DGE) of proteins and multidimensional …
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Automated data acquisition and analysis for high-resolution Fourier transform mass spectrometry of proteins and peptides
… the progress made in automating the data acquisition and data processing of MS and MS/MS data from Fourier transform ion cyclotron resonance mass spectrometers. These instruments have made great strides in the past few years, moving from labor-intensive, largely manual systems to the current …
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