Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 7 of 7 for “"Formoterol"”.
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Performance of two different types of inhalers. Influence of flow and spacer on emitted dose and aerodynamic characterisation.
… examination of three mainstream inhaled drugs Formoterol, Budesonide and Beclomethasone for treatment of asthma and COPD. The areas investigated are these which have been raised in reports and studies, where there are concern, for drug use and assessment of their use. In reporting this work the …
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Use of nanoemulsion liquid chromatography (NELC) for the analysis of inhaled drugs. Investigation into the application of oil-in-water nanoemulsion as mobile phase for determination of inhaled drugs in dosage forms and in clinical samples.
… developed and validated for the determination of formoterol in an Oxis® Turbuhaler® using pre-column fluorescence derivatisation. Although the same mobile phase was extended for separation of formoterol in urine, the formoterol peak¿s overlap with endogenous peaks meant that fluorescence detection …
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The Effect of Phosphodiesterase Inhibitors on the Induction of Gene Expression by Long-Acting beta2-Adrenoceptor Agonists and Glucocorticoids
… element luciferase reporter to the LABA, formoterol. Furthermore, PDE3 plus PDE4 inhibitors in combination prolonged and/or sensitized the ability of formoterol to induce several genes in BEAS-2B cells that have anti-inflammatory potential in the absence and presence of the glucocorticoid, …
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An in vitro investigation of the molecular effects of aging and exercise signaling within human skeletal muscle cells
… passaging protocol to represent aging in vivo. Formoterol (FORM), an exercise mimetic, was used to stimulate general exercise signaling. Four conditions were included in this study (n = 6), control (CON), aging (AGED), CON with FORM stimulation (CON+FORM), and AGED with FORM stimulation …
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Symptoms and aspects on eosinophil activity in allergic rhinitis
… we examine whether or not a topical ß2-agonist (formoterol) affect eosinophilic inflammation in allergic rhinitis. We demonstrate that the ß2-agonist neither affects symptoms and eosinophilic inflammation in allergic rhinitis nor the efficacy of a topical corticosteroid. Employing the allergen …
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Analysis of the Repeated Measurement Data using the Hierarchical Clustering and Nonlinear Regression Methods in Asthma Pharmacogenetic Study
… With using combination inhaler (budesonide/formoterol 320μg/d) for 80 days, we monitored morning and evening peak expiratory flow daily and pulmonary function every 8 weeks. Twelve SNPs from 9 candidate genes including ADCY9 132007 T>C (Ile772Met), ALOX5 -1708 G>A, CysLTR1 -634 C>T, CysLTR2 …
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The Role of Hydrocortisone on the Development and Maintenance of Ion Transport Pathways Essential to Mucociliary Clearance in Differentiated Normal Human Bronchial Epithelial Cells
… airway caliber. LABAs, such as Salmeterol and Formoterol, are effective long-acting inhaled bronchodilators. These drugs stimulate increases in cAMP which activates protein kinase A (PKA) dependent signaling pathways in airway smooth muscle, leading to relaxation and a decrease in airway …