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Showing 1 to 9 of 9 for “"Forensic DNA analysis"”.
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The development of PCR internal controls (PICs) for forensic DNA analysis
Proper interpretation of DNA profiles depends on the quality of the DNA samples, the amplification efficiency and the success of post-PCR processing. Chemicals associated with forensic samples can affect the amplification process while random errors occurring during pipetting and electrokinetic …
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Analysis of mitochondrial DNA variation in the Egyptian population and its implications for forensic DNA analysis
The genetic sequence of human mitochondrial DNA (mtDNA) is of particular interest to forensic investigations involving human identification, as well as population genetics. The current mtDNA database is lacking sufficient representatives of African mitochondrial DNA sequences compared to European …
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Algorithmic advances towards a fully automated DNA genotyping system
… Repeats (STR) genotyping is a leading tool in forensic DNA analysis. In STR genotyping, alleles in a sample are identified by measuring their lengths to form a genetic profile. Forming a genetic profile is time-consuming and labor-intensive. As the technology matures, increasing demand for …
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High-throughput Amplicon Sequencing Optimization for Downstream Prediction Purposes
Alongside short tandem repeat (STR) typing, forensic DNA phenotyping (FDP) can enhance forensic DNA analysis by inferring externally visible characteristics and biogeographical ancestry from single-nucleotide polymorphisms (SNPs). This project involves the optimization of a high-throughput amplicon …
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The assessment of forensic molecular markers for skin colour in South Africans
… the approach towards human identification. In forensic casework, the emergence of molecular phenotyping, or phenotypic prediction from DNA, has mitigated some challenges involving the unavailability of references samples for traditional forensic DNA analysis. Molecular phenotyping via SNP …
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Molecular Forensic Investigations into Animal Sexual Abuse
… indicator that sexual activity occurred, while forensic DNA analysis provides a lead to a potential suspect. After conducting a systematic literature review, no previous research investigating semen and/or DNA recovery from animals over time was found. Therefore, this pilot study aimed to assess …
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Marketised forensic DNA-profiling in England & Wales
Forensic science provision in the United Kingdom has undergone significant, though uneven, development during the past decade. In England and Wales, forensic expertise is now delivered by way of a commercial market, whilst similar provision in Scotland, and Northern Ireland, remains within the …
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The Use And Development Of Laser Microdissection To Separate Spermatozoa From Epithelial Cells For Str Analysis
Short Tandem Repeat (STR) analysis has become a valuable tool in identifying the source of biological stains, particularly from the investigation of sexual assault crimes. Difficulties in analysis arise primarily in the interpretation of mixed genotypes when cell separation of the sexual …
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Comparison of results using temperature controlled differential extraction and differential extraction using the QIAGEN EZ1 advanced
… it takes to extract the deoxyribonucleic acid (DNA) from the cells, it is hard for labs to keep up with the demand. The extraction method used is called differential extraction, where the epithelial cells from the victim are separated from the sperm cells from the perpetrator into different …