Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 25 for “"Folliculogenesis"”.
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Investigating the role of ephrins and their receptors in mouse folliculogenesis and ovulation
Follicle stimulating hormone (FSH) promotes granulosa cell (GC) proliferation, differentiation, and steroidogenesis. This series of events is critical for female fertility, and culminates in the formation of mature follicles responsive to the surge of luteinizing hormone (LH) that triggers …
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Mechanisms by which di(2-ethylhexyl) phthalate and mono(2-ethylhexyl) phthalate disrupt ovarian folliculogenesis and steroidogenesis
… are essential for normal ovarian function are folliculogenesis and steroidogenesis. Follicles are the functional units of the ovary containing the oocyte required for ovulation and fertilization and somatic cells responsible for synthesizing sex steroid hormones. Folliculogenesis is the process …
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TRANSCRIPTOME LANDSCAPE OF EARLY FOLLICULOGENESIS IN MAMMALS: UNLOCKING THE INTERPLAY MECHANISMS TO ENHANCE ART EFFICIENCY IN FERTILITY PRESERVATION
… has been successfully adopted to replicate folliculogenesis in vitro, as existing approaches remain experimental due to an incomplete understanding of the mechanisms involved, thus limiting the success of mimicking the complete folliculogenesis process in vitro. Folliculogenesis is a highly …
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Prenatal exposure to di-(2-ethylhexyl) phthalate and high-fat diet synergistically disrupts mouse fetal oogenesis and affects folliculogenesis
… weight/day) and high-fat diet on oogenesis and folliculogenesis. To fulfill that goal, female CD-1 mice were fed with a high-fat diet (45 kcal% fat) or a control diet (10 kcal% fat) one week before mating and during pregnancy and lactation. The pregnant mice were orally dosed with DEHP (20 µg/kg …
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Lineage specification of ovarian theca cells requires multi-cellular interactions via oocyte and granulosa cells
… layer, blunted steroid production, arrested folliculogenesis, and failure to form corpora lutea. Production of Dhh/Ihh in granulosa cells requires growth differentiation factor 9 (GDF9) from the oocyte. Gdf9 ablation resulted in diminished expression of Dhh, Ihh, and theca cell-specific Gli1. …
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The transgenerational effects of Di(2-ethylhexyl) phthalate on female reproduction in mice
… ancestral DEHP on ovarian steroidogenesis and folliculogenesis and how DEHP exposure affects female reproductive outcomes in the F1 – F3 generation of mice. Additionally, I investigated how prenatal and ancestral DEHP exposure disrupts gene expression and DNA methylation in juvenile mouse …
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Systemic Leptin Modulates the Expression of E-cadherin, β-catenin in the Ovary of Dietary-Induced Obese Infertile Rats
… junction, is expressed in the rat ovary during folliculogenesis. We hypothesized that systemic leptin modulates the expression of E-cadherin and β-catenin in dietary-induced obese infertile rats to reverse infertility. Female Sprague-Dawley rats were fed either regular chow diet (RCD) (n=6) or …
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Histerektomijos įtaka ankstyvojo kiaušidžių nepakankamumo rizikai. Mokslinės literatūros apžvalga /
… It will broadly discuss ovarian function - folliculogenesis and endocrine function, the hormones produced and their impact on the female body systems, not limited to the reproductive system. Ovarian failure (menopause) - normal, physiological age of onset of the process and possible symptoms …
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DEVELOPMENT OF PHYSIOLOGICAL CULTURE SYSTEMS TO ACCESS UNTAPPED OVARIAN RESERVES FOR IMPROVING REPRODUCTIVE EFFICIENCY
… fertility preservation via complete in vitro folliculogenesis is still chimerical. Recreating folliculogenesis to grow a dormant primordial follicle to the preovulatory stage in vitro remains the most coveted goal of fertility preservation programs. The ability to grow undifferentiated oocytes …
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Generating hair follicle inductive dermal papillae cells from adipose derived mesenchymal stem cells
… and to date a method of generating de novo folliculogenesis from human cells has yet to be accomplished. Existing models rely on combining 'inductive’ dermal and 'receptive’ epithelial components and placing them within a suitable model. Epithelial cells are easily obtainable from skin …
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Transcriptional profiles of cumulus-oocyte complexes related to developmental competence in bovine oocytes
During folliculogenesis, oocytes and cumulus cells undergo many morphological and physiological changes. Transcriptome data were produced from single oocytes and corresponding cumulus cells (CC) to infer the differences in the transcript abundance from fully grown versus growing phase oocytes and …
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Computer-Assisted Image Analysis of Human Ovarian Follicles: Imaging Physiologic Selection
Antral ovarian folliculogenesis involves recruitment of a cohort of small follicles, physiological selection of a dominant follicle, and ovulation. The mechanism of selection has not been precisely determined. Identification of the timing of preovulatory selection is a key component in …
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Fertility preservation of ovarian germ cells: the horse and deer models
… and molecular mechanisms related to folliculogenesis in horse and white-tailed deer species. In study one, equine ovarian tissue was used to determine the ideal ovarian fragment size for better cooling resistance under storage at 4°C. In study two, equine ovarian tissues were used to …
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Investigating mechanisms of ovotoxicity of Perfluorooctanoic acid and Zearalenone exposure and the influence of altered metabolic status on ovarian function
… primordial follicles, alters steroidogenesis and folliculogenesis, altering the estrous cycle, and blunts the ovarian response to toxicant exposure. In this dissertation, the hypothesis that altered physiological status such as obesity or heat stress would enhance ovarian sensitivity to the …
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Endocrine markers of ovarian function: Clinical and biological aspects with focus on Anti Müllerian hormone
… and closely linked to LH as a key player during folliculogenesis
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Adamts9 is critical for the development of primary ovarian follicles
… maintenance and that loss of Adamts9 leads to folliculogenesis deficiency, follicle arrest, loss of ovarian follicles and eventual female to male sex reversal after primary sex determination in juvenile and adult zebrafish.
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The role of endothelin-2 in ovulation
… loss of EDN2 prevents follicle rupture but not folliculogenesis or corpus luteum formation. RT-PCR revealed that expression of genes critical in angiogenesis and leukocyte action are not modified by Edn2-ablation, implying no significant involvement of EDN2 in these ovulatory biological …
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The immediate and long-term consequences of temporary exposure during adulthood to di(2-ethylhexyl) phthalate and diisononyl phthalate on female reproduction
… maintenance of this follicular growth, termed folliculogenesis, is imperative for maintenance of proper fertility and overall somatic health. Female fertility relies on a steady stream of maturing follicles in addition to the proper maintenance of the cyclical rise and fall of sex steroid and …
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