Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 6 of 6 for “"Follicular lymphoma"”.
-
Correlation Matrix Analysis Identifies Gene Signatures of Immune Cell Subsets and Their Interactions In Follicular Lymphoma
… cell subsets and neoplastic B cells within follicular lymphoma (FL). Using the novel technique of correlation matrix analysis (CMA) of publicly available FL whole-tumor gene expression profiling (GEP) data, we have identified signatures of immune cell subsets. Overall survival correlated …
-
Cytogenetic and molecular analysis of follicular non-Hodkin's lymphoma
… reciprocal translocation t (14;18)(q32;q21) in follicular lymphoma varies from 50% to 90% in American series. In the largest series from Europe, the translocation was present in only 21/51 (41%) of cases. The wide variety in incidence may in part be due to the method of detection used - usually …
-
Understanding the nutrient sensing branch upstream of mTORC1
… characterize the role of the Rag GTPases in follicular lymphoma. We identify recurrent, mTORC1-activating mutations in RRAGC, the gene that encodes RagC, in a large portion of follicular lymphoma samples (17%). These variants in RagC increase raptor binding and render cells partially …
-
Purging e alte dosi di chemioterapia con reinfusione di cellule staminali autologhe in linfomi non Hodgkin follicolari resistenti/refrattari
… cell transplantation (ASCT) in the management of follicular lymphoma (FL) is still debated. To evaluate the safety and efficacy of myeloablative therapy with rescue of purged or unpurged harvests in FL pts. At our institution form 1997 to 2007 28 pts with refractory/resistant FL were eligible for …
-
Harnessing synergy between BCL6 and PI3Kδ to generate a new mouse model for lymphoma
… develop autoimmunity, lymphoproliferation, and lymphoma. PIK3CD is also among the most commonly mutated genes in Diffuse Large B cell lymphoma (DLBCL). The most commonly studied mouse model of DLBCL was generated by knocking a BCL6 transgene into the Igμ locus (μHABCL-6Tg). Our lab has generated …
-
Molecular Insights of Primary Thyroid B-cell Lymphomas by Somatic Genetic and Immunogenetic Profiling
Primary thyroid lymphomas are commonly derived from a background of Hashimoto’s thyroiditis and comprise largely of extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue (EMZL) and diffuse large B-cell lymphoma (DLBCL), followed by follicular lymphoma (FL). The Du group has …