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Showing 1 to 3 of 3 for “"Follicular T helper cells"”.

  1. Elucidating the role of BCL6 in helper T cell activation, proliferation, and differentiation

    … the differentiation of germinal center (GC) B cells and follicular T helper (TFH) cells. The interaction of TFH and GC B cells is necessary for the development of high affinity antibodies specific for an invading pathogen. Germline BCL6-deficient mouse models limit our ability to study BCL6 …

    iupui Repository record for Elucidating the role of BCL6 in helper T cell activation, proliferation, and differentiation (opens in a new tab)

  2. Elucidating the Role of Antigen-presenting Cells in the Immunopathogenesis of the Porcine Reproductive and Respiratory Syndrome Virus

    … susceptibility of bone marrow-derived dendritic cells (BMDCs), monocyte-derived dendritic cells (MoDCs), and monocyte-derived macrophages (MoMΦs). After successfully differentiating and characterizing BMDCs from hematopoietic stem cells isolated from the sternum of animals, we demonstrated that …

    sask Repository record for Elucidating the Role of Antigen-presenting Cells in the Immunopathogenesis of the Porcine Reproductive and Respiratory Syndrome Virus (opens in a new tab)

  3. Pten Signaling in Regulatory T Cells and Inflammatory Disease

    Regulatory T (Treg) cells suppress CD4+ T cell responses during homeostasis and inflammation to prevent autoimmunity and other immune disorders. Although the transcriptional and epigenetic programs impacting Treg cell function have been extensively studied, the signaling and metabolic pathways …

    tenn-hsc Repository record for Pten Signaling in Regulatory T Cells and Inflammatory Disease (opens in a new tab)