Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 4 of 4 for “"FoldX"”.
-
Evolution as a design tool to inform biomolecular engineering
… by short Molecular Dynamics simulations using FoldX.
-
Discovering LC3-interacting region (LIR) motifs in hemorrhagic fever viruses: Implications for host autophagy and viral replication.
… interaction with LC3 via AlphaFold3 and FoldX analysis. Our LIR discovery pipeline identified a highly favorable interaction between LC3 and the Marburg virus nucleoprotein (MARV NP). Utilizing isothermal titration calorimetry and co-immunoprecipitation we have confirmed the interaction …
-
Engineering Signal Transduction Pathways in Bacteria
… erfolgte mit Hilfe der Algorithmen PERLA und FoldX sowie dem Programm SwissPdbViewer, basierend auf der Kristallstruktur der periplasmatischen Domäne von Tar im Komplex mit Glutamat. Obwohl diese Methode sehr vielversprechend aussah, als sie für einige Mutaten in dem Wildtyp Chemotaxis System …
-
Probing PAX6-DNA interactions using high-throughput yeast one-hybrid assays and deep mutational scanning
PAX6 is a highly conserved transcription factor essential for the correct development of the central nervous system, the pancreas, and the eye. Heterozygous deletions, nonsense, and frameshift mutations are generally well characterised as causing aniridia, while most missense variants produce a …