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Showing 1 to 3 of 3 for “"Fold Superfamilies"”.
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Structural and functional advances in the evolutionary studies of cells and viruses
… conserved protein domain structure information (fold families [FFs] and fold superfamilies [FSFs]) and ontological definitions of gene products (Gene Ontology [GO]) to reconstruct rooted trees of life (ToL), taking advantage of a genomic census of molecular structure and function in the genomes …
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A dynamic model for the evolution of protein structure
… of a protein determines its function, it is the fold, much more than the underlying protein sequence and underlying chemistry, that is evolutionarily conserved. We are interested in probing the history of life with these domain structures and glimpsing qualitative changes over time by studying a …
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Tracing history of protein domain organization, functional loops, and dipeptides with chronologies and networks
This Dissertation was approved for publication on 2022-07-14 at 09:55.