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Showing 1 to 20 of 97 for “"Focused Ultrasound"”.
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Cavitation in focused ultrasound
… is developed combining a high intensity<br/>focused ultrasound source and a pulsed-laser, for the study<br/>of cavitation in a field typical of those used for therapeutic ultrasound.<br/>The sonoptic chamber is specifically designed to avoid the formation<br/>of acoustic standing waves, known …
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Use Of Focused Ultrasound For Transcranial Sonothrombolysis
… globally each year. Use of transcranial focused ultrasound (FUS) for sonothrombolysis is a new research field for ischemic stroke treatment. If shown to be effective, FUS sonothrombolysis could become a widely available treatment option for the majority of the stroke sufferers that do not …
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Passive monitoring of high-intensity focused ultrasound
High intensity focused ultrasound (HIFU) can provide a means of noninvasive ablation or hyperthermia of tissues such as tumors. Real-time monitoring of the progression of the field distribution of the HIFU transducer during treatment is important for localizing the intersection of the beam with the …
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Focused ultrasound-mediated drug delivery to the brainstem
… needed for the treatment of brainstem glioma. Focused ultrasound combined with microbubbles can noninvasively induce temporal BBB disruption (FUS-BBBD) at the FUS-targeted brain region, allowing the trans-BBB delivery of intravenously injected agents. Focused ultrasound-mediated intranasal …
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Transcostal focused ultrasound surgery: treatment through the ribcage
… clinical application of image-guided transcostal focused ultrasound surgery (FUS) are the organ motion caused by cardiac and respiratory movements and the presence of the ribcage. Intervening ribs absorb and reflect the majority of ultrasound energy excited by an acoustic source, resulting in …
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Fast finite element methods for focused ultrasound applications
… time-domain, fast finite element solver for focused ultrasound (FUS) applications. FUS is a rapidly evolving medical technology used for tissue heating, ablation, and neuromodulation. In recent years, interest in FUS has grown significantly, especially for the treatment of cancers and brain …
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Design and Development of Single Element Focused Ultrasound Transducers
… therapy that utilizes converging high-pressure ultrasound waves at a focal point to produce cavitation and induce mechanical tissue destruction. Currently, rapid prototyped histotripsy transducers consist of multiple elements and are made using 3D printing methods. Multi-element transducers …
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Focused Ultrasound Methods for the treatment of Tendon Injuries
… tendons to achieve functional healing responses. Focused Ultrasound (FUS) methods are an attractive treatment option as they are non-invasive, utilize higher intensities for shorter durations and are targeted to a very specific treatment volume, hence inducing significant bio-effects in the tissue …
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Effects of high intensity focused ultrasound on the intervertebral disc
… was to study and try to optimise high intensity focused ultrasound treatment of the intervertebral disc. We demonstrated that it was possible to heat intervertebral discs with HIFU delivered by 50 or 5 mm diameter ultrasound transducers. Finite element studies indicated that it would be possible …
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Shear-wave imaging guidance for high-intensity focused ultrasound therapy
High-intensity focused ultrasound (HIFU) has attracted many research interests during the last three decades (since 1980s) for the precision of this treatment in the field of medical oncology and brain surgery. Even though the precision of HIFU application/exposure is particularly high, the overall …
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Real time motion tracking in image guided focused ultrasound intervention
Focused ultrasound surgery (FUS) or high intensity focused ultrasound (HIFU), is a promising technique for less- or non-invasively destroying unhealthy tissue deep inside the body, without damage to the skin or surrounding tissues. The procedure has been performed under both diagnostic ultrasound …
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Development of Histotripsy Focused Ultrasound Devices Using Rapid Prototyping Methods
Histotripsy is a nonthermal ultrasound therapy used to treat cancer noninvasively by tissue mechanical fractionation with cavitation bubble clouds. Histotripsy is conducted through focused ultrasound transducers, where the piezoceramic (PZT) plate or disc, which emits the ultrasound wave, is the …
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Advancing Transcranial Focused Ultrasound for Noninvasive Neuromodulation of Human Cortex
Ultrasound waves are mechanical undulations above the threshold for human hearing, and have been used widely in both the human body and brain for diagnostic and therapeutic purposes. Ultrasound can be controlled using specially designed transducers into a focus of a few millimeters in diameter. Low …
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Dynamics of smart materials in high intensity focused ultrasound field
… this requirement by using high intensity focused ultrasound (HIFU) as the external trigger. HIFU has a unique capability of maintaining both spatial and temporal control and propagating over long distances with reduced losses, to achieve the desired response of the smart material. Two …
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Optimized pulsing of high-intensity focused ultrasound for enhanced therapeutic window
High intensity focused ultrasound (HIFU) provides a unique modality to perform non-invasive surgeries. The thermal ablation technique relies on focusing the non-ionizing acoustic wave within soft tissues to produce a small lesion. HIFU operations are typically attempted by continuous-wave (CW) …
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Targeted Drug Delivery with Cyclodextrin-based Nanocarriers and Focused Ultrasound Triggering
… tumours using magnetic resonance imaging guided focused ultrasound (MRgFUS) to cavitate microbubbles (MBs) for increasing cell permeability and to open ‘drug nano-capsules’ to release proven active anticancer drugs directly to the tumour site with reduction of systemic drug dosage needed for the …
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Fast estimation model of pressure-temperature response for planning focused ultrasound surgery
High Intensity Focused Ultrasound (HIFU) is becoming a widely accepted modality for extracorporeal non-invasive hyperthermia and surgical procedures. Since ultrasonic transducers need to operate in various challenging body locations, the arrangement of their array elements can be optimized to …
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Propagation of High Intensity Focused Ultrasound through a Patient-specific Ribcage Model
A method of 3D modelling of high intensity focused ultrasound (HIFU) treatment through ribcage using patient data is described. This is further tested experimentally to derive at various parameters which could be indirectly useful in defining amount of energy and alteration needed in treatment …
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Shape memory polymers with improved shape recovery properties in focused ultrasound fields
… Among the various activation mechanisms, focused ultrasound (FUS) has emerged as a promising non-invasive and spatially selective stimulus, capable of inducing localized heating via viscous polymer chain shearing. However, the material design strategies enabling efficient and rapid shape …
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Focused Ultrasound Extraction (FUSE) for Formalin-Fixed, Paraffin Embedded (FFPE) DNA Extraction
… applications. Here, we propose the use of focused ultrasound extraction (FUSE) technology for improved DNA extraction from FFPE tissue. FUSE generates a dense bubble cloud of acoustic cavitation capable of ablating tissue into an acellular lysate. FUSE treatment was applied to …
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