Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 6 of 6 for “"Focal cortical dysplasia"”.
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Investigation of the GATOR1 complex genes in focal cortical dysplasia and focal epilepsy
… genes have been found in patients with familial focal epilepsy and focal cortical dysplasia (FCD) type II. Heterozygous patients are affected with variable severity, variable foci and incomplete penetrance. The function of these genes and the mechanisms of how their mutation cause the disease are …
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A deep learning approach to focal cortical dysplasia segmentation in children with medically intractable epilepsy
… the cognition and quality of life of children. Focal Cortical Dysplasia (FCD) is one of the most common causes of medically intractable epilepsy. FCD may be amenable to surgical resection to achieve seizure freedom. By improving the detection of lesions such as FCD, the surgical outcome of these …
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Identifying lesions in paediatric epilepsy using morphometric and textural analysis of magnetic resonance images
… Imaging (MRI) sequences to identify features of Focal Cortical Dysplasia (FCD) in patients with MRIvisible FCD. We aim to use a computer-aided diagnosis system to identify epileptogenic lesions with a combination of established morphometric features and textural analysis using Gray-Level …
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Generation of focal Depdc5 knockout mouse model and implications for focal epilepsy
… identified gene associated with familial focal epilepsy and malformations of cortical development. It is also associated with an increased risk of Sudden-Unexplained Death in Epilepsy (SUDEP). It remains unknown whether seizures due to DEPDC5 loss are a result of in utero cortical …
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Paediatric epilepsy surgery in a middle-income country: the red cross war memorial children's hospital experience
… finding in anterior temporal lobectomy (ATL) was focal cortical dysplasia (FCD), found in 11 patients (57.9%). The periinsular hemispherotomy (PIH) cases had equal numbers of FCD and Rasmussen's encephalitis in 4 patients (44.4%). The number of FCD in this series is much higher than in …
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Memory Performance in Children with Temporal Lobe Epilepsy: Neocortical vs. Dual Pathologies
This study investigated memory in children with temporal lobe epilepsy and the ability to discern hippocampal dysfunction with conventional memory tests that are typically used to detect more global memory impairment. All data was obtained retrospectively from the epilepsy surgery program at a …