Global ETD Search
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Showing 1 to 3 of 3 for “"Fn14"”.
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Exploring a Novel Mechanism of Reguation of the TNFR Family Member FN14
Fibroblast growth factor-inducible 14 (FN14) is a highly inducible cytokine receptor linked to a number of intracellular signaling pathways, including the nuclear factor-kappaB (NFkB) and mitogen-activated protein kinase (MAPK) pathways, as well as to physiological processes, such as angiogenesis, …
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TWEAK/Fn14 Pathway is Activated by Hypoxia and is a Novel Mediator of Retinal Neovascularization
… receptor, fibroblast growth factor inducible 14 (Fn14), have been implicated in angiogenesis but their role in retinal diseases is largely unknown. The purpose of my study was to evaluate the role of TWEAK/Fn14 pathway in NV. I used mouse model of oxygen-induced retinopathy (OIR), which is …
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Investigating the use of omega three fish oils as protective agents against cytokine-induced skeletal muscle damage
… TNFa and TWEAK receptors (TGFpRII,TNFRI and Fn14 respectively).ConclusionOur findings suggest ERA and DMA are potentially useful 'neutriceuticals' that reducefibrosis and improve muscle repair in vivo. Their mode of action is PPARydependent in inflammatory skeletal damage (TNFa and TWEAK) but …