Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 3 of 3 for “"Fluoropyrimidines"”.
-
Novel Oligomeric Fluoropyrimidines and Their Efficacy for the Treatment of Colorectal Carcinoma Independent of p53 Mutation
… aimed to demonstrate that our novel oligomeric fluoropyrimidines are able to overcome these limitations of 5-FU in vivo. The results indicate that F10 and other fluoropyrimidines showed little-to-no p53 dependency in in vivo xenografts. While F10 displayed the same p53 independency in vitro when …
-
INVESTIGATION OF ANTIBIOFILM AND ANTIVIRULENCE ACTIVITY OF 5-FLUOROCYTOSINE IN ESCHERICHIA COLI
… in P. aeruginosa and E. coli, I evaluated fluoropyrimidines 5-fluorocytosine (5-FC), 5-fluorouracil (5-FU), and 5-fluorouridine (5-FUrd) as modulators of biofilm determinants in E. coli. I found that 5-FC showed lower antimicrobial activity to the E. coli laboratory strain MG1655 than 5-FU …
-
An investigation of the release of 5-fluorouracil from ointment bases
<p>During the several years in which this therapy has been developed and evaluated, as standard dermatological preparation has not been available. The objective of the present work was to study the release of 5-FU from various ointment bases and to attempt to determine the type of base which would …