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Showing 1 to 1 of 1 for “"Fluorinated Substrate Analogs"”.

  1. Towards Fluorinated Substrate Analogs and N-Acylated 2-Aminopyrimidine Inhibitors of Lipoxygenases

    Haycock, Meghan LynnUniversité d'Ottawa / University of Ottawa2014

    … in which the methylene hydrogen atoms on the substrate were replaced with a moiety lacking a labile hydrogen atom, such as fluorine. This would allow the LOX enzyme to remain in an active form, while preventing enzyme turnover. This preliminary work will enable the assessment of their activity …

    ottawa-retro Repository record